catalog number :
MBS538288
products type :
Recombinant Protein
products full name :
IP10 protein
products short name :
IP10
products name syn :
IP-10 protein; gamma-Interferon Inducible Protein 10 protein; crg-2 protein; IP10; IP-10; CXCL10 protein; IP 10 protein; IP 10
other names :
IP-10; C-X-C motif chemokine 10; C-X-C motif chemokine 10; chemokine (C-X-C motif) ligand 10; 10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; C7; Interferon-gamma induced protein CRG-2; Small-inducible cytokine B10
products gene name :
IP10
other gene names :
Cxcl10; Cxcl10; C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10; Crg2; Ifi10; Inp10; Scyb10; Gamma-IP10; IP-10
uniprot entry name :
CXL10_MOUSE
sequence :
Region of IP10 protein corresponding to amino acids VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK EMSKRSP.
form :
Sterile filtered through a 0.2 um filter. Lyophilized with no additives.
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Protein Type: Recombinant. Biological Significance: IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Bioactivity: Determined by its ability to chemoattract human T-lymphoytes using a concentration of 10-50 ng/ml. Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
other info2 :
Expression System: E Coli
products categories :
Cytokines & Growth Factors
products description :
Purified recombinant Human IP10 protein
ncbi acc num :
AAA75249.1
ncbi mol weight :
10,789 Da
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway 1168363!!Chemokine Signaling Pathway 99271!!Chemokine Signaling Pathway 672435!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 1168361!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytosolic DNA-sensing Pathway 125146!!Cytosolic DNA-sensing Pathway 124833!!G Alpha (i) Signalling Events Pathway 1168392