catalog number :
MBS538277
products type :
Recombinant Protein
products full name :
CTGF protein
products short name :
CTGF
products name syn :
CCN2 protein; HCS24 protein; Hypertrophic chondrocyte-specific protein 24 protein; Connective Tissue Growth Factor protein
other names :
connective tissue growth factor; Connective tissue growth factor; connective tissue growth factor; connective tissue growth factor; Connective tissue growth factor
products gene name :
CTGF
other gene names :
CTGF; CTGF; CCN2
uniprot entry name :
Q98TQ8_CHICK
sequence :
Region of CTGF protein corresponding to amino acids MGKKCIRTPK ISKPIKFELS GCTSMKTYRA KFCGVCTDGR CCTPHRTTTL PVEFKCPDGE VMKKNMMFIK TCACHYNCPG DNDIFESLYY RKMYGDMA.
form :
Lyophilized from 10 mM NaC2H3O2, pH 6.0. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.
concentration :
5ug lyophilized
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Protein Type: Recombinant. Biological Significance: CTGF is a member of the CCN family of secreted cysteine rich regulatory proteins and is the major mitogenic and chemoattractant protein produced by umbilical vein and vascular endothelial cells. CTGF stimulates the proliferation and differentiation of chondrocytes, induces angiogenesis, promotes cell adhesion of fibroblasts, endothelial, and epithelial cells, and binds to IGF, TGF beta1, and BMP-4. Cell migration and adhesion are signaled through binding to specific cell surface integrins and to heparin sulfate proteoglycans CTGF (98 a.a.), a lower molecular weight isoform containing the C-terminal portion of the full length CTGF protein, exerts full heparin binding, cell adhesion, and mitogenic CTGF activity. Bioactivity: Determined by the dose-dependent stimulation of the proliferation of HUVEC cells. The expected ED50 for this effect is 1.0-2.0 ug/ml. Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
other info2 :
Expression System: E Coli
products categories :
Cytokines & Growth Factors
products description :
Purified recombinant Human CTGF protein
ncbi acc num :
NP_989605.1
ncbi gb acc num :
NM_204274.1
ncbi mol weight :
11.2 kDa