catalog number :
MBS538163
products type :
Recombinant Protein
products full name :
HIV1 gp120 protein
products short name :
[HIV1 gp120]
products name syn :
[HIV-1 gp120 protein; HIV 1 gp120; Glycoprotein 120 protein; SU protein; gp120 protein; HIV1 gp120; gp120 glycoprotein protein; HIV 1 gp120 protein; Envelope surface glycoprotein gp120 protein; Surface protein protein; Human Immunodeficiency Virus 1 protein; HIV-1 gp120]
products gene name :
[HIV1 gp120]
host :
Recombinant gp120 (HIV-1 IIIB produced in mammalian cells, CHO)
purity :
> 95% by SDS-PAGE
form :
Supplied frozen in PBS buffer with no preservatives. MW= 120 kD
concentration :
1.0 mg/ml
storage stability :
Ships on dry ice. Upon receipt store at -75°C or lower. Avoid multiple freeze/thaws.
tested application :
In-vitro Diagnostics; CD4 Binding; T-Cell Activation.
app notes :
Optimal conditions to be determined by end user.
other info1 :
Biohazard: Use standard laboratory precautions when handling this material. Species: Viral. Bioactivity: This protein binds to human T-cell receptor CD4 in ELISA and Western ELISA as determined by CD4/gp120/Anti-gp120 mAb-peroxidase capture ELISA. This protein activates human T-Lymphocytes (CD4+, CD4-), in vitro, as measured by RNA synthesis during G0 to G1.
products categories :
Infectious Disease
products description :
Description: Purified full length recombinant HIV1 gp120 protein-IIIB strain. Biological Significance: Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120 kilodaltons. gp120 is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry.