catalog number :
MBS538090
products type :
Recombinant Protein
products full name :
HIV1 gp41 protein
products short name :
HIV1 gp41
products name syn :
SU antigen; Glycoprotein 41 antigen; gp41 antigen; HIV-1 gp41; Envelope surface glycoprotein gp41 antigen; HIV 1 gp41 protein; HIV1 gp41; HIV-1 gp41 antigen; Surface protein antigen; HIV 1 gp41 antigen; HIV-1 gp41 protein; HIV 1 gp41; gp41 glycoprotein antigen; Human Immunodeficiency Virus 1 antigen
products gene name :
HIV1 gp41
form :
Supplied frozen in 1M Urea, 0.02M Na3PO4, with 0.5M NaCl, pH 7.4.
storage stability :
Aliquot and store at -70 degree C or lower. Avoid repeated freeze/thaw cycles
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Protein Type: Recombinant. Biological Significance: HIV gp41 is a glycoprotein subunit that remains non-covalently-bound to gp120, and provides the second step by which HIV enters the cell. It is originally buried within the viral envelope, but, when gp120 binds to a CD4, gp120 changes its conformation, causing gp41 to become exposed, where it can assist in fusion with the host cell. The Env gene does not, in fact, code for gp120 and gp41, but for a precursor to both, gp160. During HIV reproduction, the host cell's own enzymes cleave gp160 into gp120 and gp41.
other info2 :
Expression System: Yeast. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
products categories :
Infectious Disease
products description :
Purified recombinant HIV1 gp41 protein
products references :
Analysis of the HIV-1 gp41 specific immune response using a multiplexed antibody detection assay; David Opalka, Antonello Pessi, Elisabetta Bianchi, Gennaro Ciliberto, William Schleif, Michael McElhaugh, Renee Danzeisen, Romas Geleziunas, Michael Miller, Debra M. Eckert, David Bramhill, Joseph Joyce, James Cook, William Magilton, John Shiver, Emilio Emini, Mark T. Esser (Journal of Immunological Methods: Volume: 287 Issue: 1-2 Page: 49-65 DOI: 10.1016/j.jim.2004.01.016)