protein

S100 protein (Bovine)

MBS537934

0.01 mg

335 USD

Recombinant Protein

S100 protein (Bovine)

S100

SB-100 protein; SB 100; SB 100 protein; S-100 BB Protein; S-100 Protein; S100B; SB-100

S100 calcium binding protein, beta (neural), isoform CRA_a; Protein S100-B; protein S100-B; S100 calcium binding protein B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B

S100

S100B; S100B; NEF; S100; S100-B; S100beta

S100B_HUMAN

Bovine

92

Lyophilized from 10mM TRIS-HCl, with 1mM EGTA.

Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -80 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC), Radioimmunoassay (RIA), Western Blot (WB)

Protein Type: Recombinant. Biological Significance: S100 calcium binding protein B or S100B is a protein of the S-100 protein family. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3.

Expression System: E Coli

Cancer

Purified Recombinant S100 protein (Bovine)

119629675

EAX09270.1

P04271

10,713 Da

Activated TLR4 Signalling Pathway 106400!!Advanced Glycosylation Endproduct Receptor Signaling Pathway 187092!!Cytosolic Sensors Of Pathogen-associated DNA Pathway 576255!!DEx/H-box Helicases Activate Type I IFN And Inflammatory Cytokines Production Pathway 833822!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!MyD88 Cascade Initiated On Plasma Membrane Pathway 205107!!MyD88 Dependent Cascade Initiated On Endosome Pathway 187081!!MyD88-independent TLR3/TLR4 Cascade Pathway 106401!!MyD88:Mal Cascade Initiated On Plasma Membrane Pathway 106390

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]

0.01 mg

335 USD