This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
protein
product name :
ApoA-II protein
catalog :
MBS537856
quantity :
1 mg
price :
395 USD
product information
catalog number :
MBS537856
products type :
Native Protein
products full name :
ApoA-II protein
products short name :
ApoA-II
products name syn :
Apolipoprotein A ll protein; ApoA2 protein; Apo AII protein; ApoA II protein
other names :
apolipoprotein A-II preproprotein; Apolipoprotein A-II; apolipoprotein A-II; apolipoprotein A-II; Apolipoprotein A2
products gene name :
ApoA-II
other gene names :
APOA2; APOA2; apoAII; Apo-AII; ApoA-II; Apo-AII; ApoA-II; ProapoA-II
uniprot entry name :
APOA2_HUMAN
host :
Human
sequence length :
100
purity :
> 95% pure
form :
Supplied as frozen liquid in 10mM NH4HC03 buffer, pH 7.4. Keep antigen concentration >1 mg/ml
storage stability :
Aliquot and store at -70 degree C. Avoid repeated freeze/thaw cycles
other info1 :
Source Note: Human plasma. Protein Type: Native. Biological Significance: 25% of Apo A in HDL is Apo AII. Levels of Apo AII in normal plasma range from 30-50 mg per 100 ml. The physiological role of the protein is unknown. Alcohol consumption, however, increases Apo AII levels.
other info2 :
Biohazard Information: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc,and negative for anti-HIV 1 & 2. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
products categories :
Nutrition & Metabolism; Native Protein
products description :
Purified native Human ApoA-II protein
ncbi gi num :
4502149
ncbi acc num :
NP_001634.1
ncbi gb acc num :
NM_001643.1
uniprot acc num :
P02652
ncbi mol weight :
17.4 kDa
ncbi pathways :
Chylomicron-mediated Lipid Transport Pathway (106157); Complement And Coagulation Cascades Pathway (198880); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); PPARA Activates Gene Expression Pathway (530749)
ncbi summary :
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]
uniprot summary :
APOA2: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Belongs to the apolipoprotein A2 family. Protein type: Endoplasmic reticulum; Secreted; Secreted, signal peptide; Lipid-binding. Chromosomal Location of Human Ortholog: 1q23.3. Cellular Component: chylomicron; endoplasmic reticulum lumen; early endosome; extracellular region; cytosol. Molecular Function: lipid transporter activity; protein binding; protein homodimerization activity; lipase inhibitor activity; protein heterodimerization activity; cholesterol transporter activity; cholesterol binding; phospholipid binding; phosphatidylcholine binding; high-density lipoprotein binding; lipid binding; apolipoprotein receptor binding. Biological Process: positive regulation of catalytic activity; phototransduction, visible light; viral reproduction; protein folding; negative regulation of cholesterol transport; response to glucocorticoid stimulus; regulation of protein stability; diacylglycerol catabolic process; positive regulation of lipid catabolic process; cellular lipid metabolic process; negative regulation of lipase activity; phospholipid efflux; negative regulation of lipid catabolic process; regulation of cholesterol absorption; response to glucose stimulus; retinoid metabolic process; response to drug; cholesterol metabolic process; organ regeneration; protein amino acid oxidation; phospholipid catabolic process; positive regulation of interleukin-8 biosynthetic process; lipoprotein metabolic process; cholesterol efflux; negative regulation of cytokine secretion during immune response; cholesterol homeostasis; triacylglycerol metabolic process; reverse cholesterol transport; response to estrogen stimulus; peptidyl-methionine modification; phosphatidylcholine biosynthetic process; acute inflammatory response. Disease: Hypercholesterolemia, Familial
size1 :
1 mg
price1 :
395 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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