catalog number :
MBS537851
products type :
Native Protein
products full name :
Lipase protein
products short name :
Lipase
products name syn :
Lipase Enzyme
other names :
lipase; Pancreatic triacylglycerol lipase; pancreatic triacylglycerol lipase; pancreatic lipase
other gene names :
PNLIP; PNLIP; PL; PTL; PNLIPD; PL; PTL; Pancreatic lipase
uniprot entry name :
LIPP_HUMAN
form :
100 mM Tris, pH 8.0, with 100 mM NaCl, 1mM Benzamidine and 1mM CaCl2.
concentration :
1.7 mg/ml
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Source Note: Human pancreas. Protein Type: Native. Biological Significance: A lipase is a water-soluble enzyme that catalyzes the hydrolysis of ester chemical bonds in water-insoluble lipid substrates. Lipases are a subclass of the esterases. They perform essential roles in the digestion, transport and processing of dietary lipids in most, if not all, living organisms. Genes encoding lipases are even present in certain viruses.
products categories :
Proteases, Inhibitors, Native Protein
products description :
Purified native Human Lipase protein
ncbi acc num :
AAA60129.1
ncbi mol weight :
51,157 Da
ncbi pathways :
Acylglycerol Degradation Pathway (413388); Acylglycerol Degradation Pathway (468272); Digestion Of Dietary Lipid Pathway (106112); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Lipid Digestion, Mobilization, And Transport Pathway (106111); Metabolic Pathways (132956); Metabolism Pathway (477135)
ncbi summary :
This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]
uniprot summary :
PNLIP: a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]. Protein type: Secreted, signal peptide; EC 3.1.1.3; Lipid Metabolism - glycerolipid; Hydrolase; Secreted. Chromosomal Location of Human Ortholog: 10q26.1. Cellular Component: extracellular region. Molecular Function: triacylglycerol lipase activity; metal ion binding. Biological Process: phototransduction, visible light; cholesterol absorption; retinoid metabolic process; lipid digestion; lipid catabolic process. Disease: Pancreatic Lipase Deficiency