catalog number :
MBS537846
products type :
Native Protein
products full name :
alpha 1 Acid Glycoprotein protein
products short name :
alpha 1 Acid Glycoprotein
products name syn :
alpha-1-Acid-Glycoprotein; Orosomucoid protein; ORM protein; AGP protein; AAG protein; alpha-1-Acid Glycoprotein protein; A1AGP protein; A1-AGP protein; alpha 1 Acid Glycoprotein
other names :
alpha-1-acid glycoprotein; Alpha-1-acid glycoprotein; alpha-1-acid glycoprotein; orosomucoid 1; Orosomucoid; OMD
other gene names :
Orm1; Orm1; AGP; OMD; Orm; Agpa1; OMD
uniprot entry name :
A1AG_RAT
form :
Supplied as a lyophilised powder.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Source Note: Human plasma. Protein Type: Native. Biological Significance: Clinically, alpha 1 acid glycoprotein is an acute-phase reactant that together with haptoglobin is an indicator of acute inflammation. The alpha 1 acid glycoprotein:haptolobin ratio is useful in studies of bone marrow disorders, hemolytic processes and metastases.
other info2 :
Biohazard Information: Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
products categories :
Immunology; Native Protein
products description :
Purified native Human alpha 1 Acid Glycoprotein protein
ncbi acc num :
NP_445740.1
ncbi gb acc num :
NM_053288.1
ncbi summary :
an acute phase reactant protein; may have a role in the acute inflammation response [RGD, Feb 2006]
uniprot summary :
ORM1: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Belongs to the calycin superfamily. Lipocalin family. Protein type: Secreted, signal peptide; Secreted. Cellular Component: extracellular space. Molecular Function: drug binding. Biological Process: response to drug; response to vitamin E; organ regeneration; regulation of immune system process; transport; acute-phase response; response to lipopolysaccharide; chronic inflammatory response to antigenic stimulus; response to organic cyclic substance; acute inflammatory response to antigenic stimulus