catalog number :
MBS537747
products type :
Native Protein
products full name :
Complement C5b, 6 complex protein
products short name :
Complement C5b, 6 complex
products name syn :
Anaphylatoxin C5b protein; C5 protein; Complement C5 protein; Complement C5b protein; Complement C5 precursor protein; Complement component 5 protein; CPAMD4 protein; C5b6 protein
purity :
>=98% by SDS-PAGE
form :
Supplied as a frozen liquid with 10 mM HEPES and 120 mM NaCl, pH 7.2
concentration :
0.22 mg/ml
storage stability :
Store at -70 degree C or below. Avoid freeze/thaw cycles. To use: Thaw product at 37 degree C and Mix Well. Avoid repeat freeze/thaw cycles.
other info1 :
Source Note: Normal human serum. Protein Type: Native. Biological Significance: Complement C5b, 6 complex, is a product of complement activation of C5 and an intermediate in the formation of the C5b-9 membrane attack complex (MAC) of complement. Each pathway of complement generates proteolytic enzyme complexes (C3/C5 convertases) which are bound to the target surface. These enzymes cleave a peptide bond in the larger alpha chain of C5 releasing the highly potent anaphylatoxin C5a (74 amino acids) and activating C5b.This is the only proteolytic step in the assembly of the C5b-9 complex.
other info2 :
Biohazard Information: This protein is purified from human plasma, therefore precautions appropriate for handling any blood-derived product must be use. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product. Fuctional activity: 31,000 Units/mg
products categories :
Immunology; Native Protein; Complements
products description :
Purified native Complement C5b, 6 complex protein
ncbi mol weight :
285 kDa