protein

ApoH protein

MBS537648

1 mg

865 USD

Native Protein

ApoH protein

ApoH

Apo-H protein; beta 2 Glycoprotein 1; Apolipoprotein H; Apo H protein; B2GP protein; beta-2 Glycoprotein 1 protein

beta-2-glycoprotein 1; Beta-2-glycoprotein 1; beta-2-glycoprotein 1; apolipoprotein H (beta-2-glycoprotein I); APC inhibitor; Activated protein C-binding protein; Anticardiolipin cofactor; Apolipoprotein H; Apo-H; Beta-2-glycoprotein I; B2GPI; Beta(2)GPI

ApoH

APOH; APOH; BG; B2G1; B2GP1; B2G1; Apo-H; B2GPI; Beta(2)GPI

APOH_HUMAN

Human

345

> 96% pure

Lyophilized from 20mM NH4HC03 buffer.

500ug per vial (lyophilized)

Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

User optimized

Source Note: Human serum. Protein Type: Native. Biological Significance: Apolipoprotein H (Apo-H) is a multifunctional apolipoprotein. One of its functions is to bind cardiolipin. When bound the structure of cardiolipin and Apo-H both undergo large changes in structure.

Cardiac Markers; Native Protein

Purified native Human ApoH protein

153266841

NP_000033.2

NM_000042.2

P02749

50 kDa

Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq, Jul 2008]

APOH: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. Protein type: Secreted; Lipid-binding; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q24.2. Cellular Component: extracellular matrix; extracellular space; chylomicron; cell surface. Molecular Function: heparin binding; identical protein binding; protein binding; phospholipid binding; glycoprotein binding; lipid binding. Biological Process: negative regulation of myeloid cell apoptosis; negative regulation of angiogenesis; negative regulation of fibrinolysis; triacylglycerol metabolic process; positive regulation of blood coagulation; negative regulation of endothelial cell proliferation; negative regulation of blood coagulation; positive regulation of lipoprotein lipase activity; triacylglycerol transport; blood coagulation, intrinsic pathway; plasminogen activation; regulation of fibrinolysis

1 mg

865 USD