product summary
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company name :
MyBioSource
product type :
protein
product name :
alpha 1 Antichymotrypsin protein
catalog :
MBS537396
quantity :
10 mg
price :
2030 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS537396
products type :
Native Protein
products full name :
alpha 1 Antichymotrypsin protein
products short name :
alpha 1 Antichymotrypsin
products name syn :
alpha-1-Antichymotrypsin; alpha-1 Antichymotrypsin protein; A1ACT protein; A1-ACT protein; alpha 1 Antichymotrypsin; alpha-1-Antichymotrypsin protein
other names :
alpha-1-antichymotrypsin; Alpha-1-antichymotrypsin; alpha-1-antichymotrypsin; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; Cell growth-inhibiting gene 24/25 protein; Serpin A3
other gene names :
SERPINA3; SERPINA3; ACT; AACT; GIG24; GIG25; AACT; ACT
uniprot entry name :
AACT_HUMAN
host :
Human
sequence length :
423
purity :
> 90% pure
form :
Lyophilized from 0.02M TRIS buffer, pH 7.5, with 0.15M NaCl.
concentration :
10 mg per vial; lyophilized
storage stability :
Store at 4 degree C.
tested application :
User optimized
other info1 :
Source Note: Human serum/plasma. Protein Type: Native. Biological Significance: Alpha 1-antichymotrypsin is an alpha globulin glycoprotein that is a member of the serpin superfamily. It inhibits the activity of certain enzymes called proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving them into a different shape or conformation. This activity protects some tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes.
products categories :
Proteases, Inhibitors, Native Protein
products description :
Purified native Human alpha 1 Antichymotrypsin protein
ncbi gi num :
50659080
ncbi acc num :
NP_001076.2
ncbi gb acc num :
NM_001085.4
uniprot acc num :
P01011
ncbi mol weight :
68 kDa
ncbi pathways :
Selenium Pathway (198825)
ncbi summary :
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]
uniprot summary :
SERPINA3: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Belongs to the serpin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 14q32.1. Cellular Component: extracellular space; extracellular region; intracellular; nucleus. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; DNA binding. Biological Process: regulation of lipid metabolic process; maintenance of gastrointestinal epithelium; acute-phase response; inflammatory response
size1 :
10 mg
price1 :
2030 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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