product summary
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company name :
MyBioSource
product type :
protein
product name :
VWF protein
catalog :
MBS537335
quantity :
0.1 mg
price :
800 USD
more info or order :
product information
catalog number :
MBS537335
products type :
Native Protein
products full name :
VWF protein
products short name :
VWF
products name syn :
Von Willebrand Factor Protein
other names :
von Willebrand factor; von Willebrand factor; von Willebrand factor; von Willebrand factor; von Willebrand antigen 2Alternative name(s):von Willebrand antigen II
products gene name :
VWF
other gene names :
VWF; VWF; VWD; F8VWF; F8VWF; vWF
uniprot entry name :
VWF_HUMAN
host :
Human
sequence length :
2813
purity :
> 95% pure
form :
25mM sodium citrate, 100mM NaCl, 100mM Glycine, pH 6.8.
storage stability :
Aliquot and store at -80 degree C or lower. Avoid repeated freeze/thaw cycles
tested application :
User optimized
other info1 :
Source Note: Human serum/plasma. Protein Type: Native. Biological Significance: Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation. The mature plasma protein is composed of apparently identical subunits (Mr=260,000) which are held together by disulfide bonds. The circulating vWF molecule ranges in size from dimers (Mr=520,000) to extremely large multimers (Mr>10,000,000). During normal hemostasis, the larger multimers of vWF are responsible for facilitating platelet plug formation by forming a bridge between platelet glycoprotein IB and exposed collagen in the subendothelium.
other info2 :
Biohazard Information: Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
products categories :
Cancer; Native Protein
products description :
Purified native Human VWF protein
ncbi gi num :
340356
ncbi acc num :
AAB59458.1
uniprot acc num :
P04275
ncbi mol weight :
260 kDa
ncbi pathways :
Blood Clotting Cascade Pathway 198840!!Complement And Coagulation Cascades Pathway 198880!!Complement And Coagulation Cascades Pathway 83073!!Complement And Coagulation Cascades Pathway 484!!ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!Formation Of Fibrin Clot (Clotting Cascade) Pathway 106057
ncbi summary :
The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
800 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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