protein

MMP9 protein

MBS537325

0.005 mg

685 USD

Recombinant Protein

MMP9 protein

MMP9

MMP9; Matrix Metalloproteinase 9 Protein; MMP9 Protein; MMP-9 protein; MMP-9; MMP 9 Protein; MMP 9 protein; MMP 9; MMP9 Recombinant Protein

matrix metalloproteinase-9 preproprotein; Matrix metalloproteinase-9; matrix metalloproteinase-9; matrix metallopeptidase 9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB

MMP9

MMP9; MMP9; GELB; CLG4B; MMP-9; MANDP2; CLG4B; MMP-9; GELB

MMP9_HUMAN

Human

707

> 90% pure

50mM HEPES, 10mM CaCl2, 20% glycerol, with 0.005% BRIJ-35 detergent, pH 7.5.

Aliquot and store at -70 degree C or lower. Avoid repeated freeze/thaw cycles

User optimized

Protein Type: Recombinant. Biological Significance: Matrix metallopeptidase 9 (MMP9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is an enzyme that in humans is encoded by the MMP9 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.

Expression System: Mammalian cells. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Proteases, Inhibitors, & Enzymes

Purified recombinant Human MMP9 protein

74272287

NP_004985.2

NM_004994.2

P14780

83 kDa

AGE/RAGE Pathway 698754!!Activation Of Matrix Metalloproteinases Pathway 576264!!Angiogenesis Pathway 198772!!Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway 730306!!Axon Guidance Pathway 105688!!Bladder Cancer Pathway 83115!!Bladder Cancer Pathway 527!!CXCR4-mediated Signaling Events Pathway 137910!!Collagen Degradation Pathway 730309!!Collagen Formation Pathway 645288

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]

0.005 mg

685 USD