catalog number :
MBS537321
products type :
Native Protein
products full name :
Myoglobin protein (cardiac)
products short name :
[Myoglobin]
products name syn :
[Heart Myoglobin Protein]
other names :
[myoglobin; Myoglobin; myoglobin; myoglobin]
other gene names :
[MB; MB; PVALB; myoglobgin]
uniprot entry name :
MYG_HUMAN
purity :
> 95% (by SDS-PAGE)
form :
Supplied as a liquid in PBS, pH 7.5, with 0.09% NaN 3 as a preservative
concentration :
3.5mg/ml by Lowry
storage stability :
Store at 4 degree C. DO NOT FREEZE.
tested application :
User optimized
other info1 :
Species: Human. Source: Prepared from human heart tissue. Protein Type: Native. Biological Significance: Myoglobin is an iron- and oxygen-binding protein found in the muscle tissue of vertebrates in general and in almost all mammals. It is related to hemoglobin, which is the iron- and oxygen-binding protein in blood, specifically in the red blood cells. The only time myoglobin is found in the bloodstream is when it is released following muscle injury.
other info2 :
Grade: Ultra Pure. Contaminants: 4-12% Bis Tris NuPage gel, SDS-PAGE reduced shows one brand corresponding to the molecular weight of Myoglobin. Biohazard: Non-reactive for HIV-1/HCV/HBV by NAT, HBsAg, HCV Ab, HIV 1&2 Ab, and RPR by currently approved FDA methods. Use appropriate laboratory precautions when handling this product.
products categories :
Cardiac Markers; Native Protein
products description :
Purified native Human Myoglobin protein (cardiac)
ncbi acc num :
NP_976312.1
ncbi gb acc num :
NM_203378.1
ncbi mol weight :
17,184 Da
ncbi pathways :
Effects Of Nitric Oxide Pathway (920994)
ncbi summary :
This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
uniprot summary :
MB: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Belongs to the globin family. Protein type: Carrier. Chromosomal Location of Human Ortholog: 22q13.1. Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity. Biological Process: slow-twitch skeletal muscle fiber contraction; response to hydrogen peroxide; oxygen transport; heart development; brown fat cell differentiation; response to hormone stimulus; response to hypoxia; enucleate erythrocyte differentiation