protein

Transferrin protein (HRP)

MBS537254

1 mg

280 USD

Native Protein

Transferrin protein (HRP)

Transferrin

TF protein; beta 1 metal binding globulin protein; Siderophilin protein; Apotransferrin protein; Serotransferrin precursor protein; DKFZp781D0156 protein; PRO2086 protein; PRO1400 protein; PRO1557 protein

transferrin; Serotransferrin; serotransferrin; transferrin; Beta-1 metal-binding globulin; Siderophilin

TF; TF; TFQTL1; PRO1557; PRO2086; Transferrin

TRFE_HUMAN

Human

698

Transferrin protein (HRP) was purified by selective precipitation and tandem chromatography followed by dialysis.

Supplied lyophilzed in 20mM Potassium Phosphate, 150mM Sodium Azide Chloride, pH 7.2, 10mg/ml BSA, with 0.01% Gentamicin Sulfate as preservative. Reconstitute with 1.0ml of deionized water. Do Not Add Sodium Azide!

1.0 mg, lyophilized

Ships ambient or refridgerated. Upon receipt store at 4 degree C prior to reconstitution. For longer storage, aliquot and store at -20 degree C. Stable for serveral weeks at 4 degree C as an undiluted liquid.

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Source Note: Human serum. Protein Type: Native

Tag/Conjugate: HRP. Additional Remarks: A single precipitin arc was observed against anti-Peroxidase, anti-Human Transferrin and anti-Human serum, when assayed by Immunoelectrophoresis.

Nutrition & Metabolism; Native Protein; Conjugated Proteins

Purified Recombinant Human Transferrin protein (HRP)

248648

AAB22049.1

P02787

EPHB Forward Signaling Pathway (138047); HIF-1 Signaling Pathway (695200); HIF-1-alpha Transcription Factor Network Pathway (138045); Hemostasis Pathway (106028); Iron Metabolism In Placenta Pathway (672461); Iron Uptake And Transport Pathway (187191); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050)

This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]

TF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Defects in TF are the cause of atransferrinemia (ATRAF). Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Belongs to the transferrin family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 3q22.1. Cellular Component: extracellular space; cell surface; cytoplasmic membrane-bound vesicle; early endosome; extracellular region; coated pit; recycling endosome; perinuclear region of cytoplasm; endocytic vesicle; late endosome; apical plasma membrane; basal plasma membrane; endosome membrane; vesicle. Molecular Function: protein binding; ferric iron binding; ubiquitin protein ligase binding. Biological Process: retinal homeostasis; platelet activation; platelet degranulation; cellular iron ion homeostasis; transferrin transport; blood coagulation; transmembrane transport. Disease: Atransferrinemia

1 mg

280 USD