catalog number :
MBS536580
products type :
Native Protein
products full name :
Filamentous Hemagglutinin (Bordetella Pertussis)
products short name :
[Filamentous Hemagglutinin]
products name syn :
[FHA; Bordetella Pertussis; Purified FHA]
other names :
[filamentous hemagglutinin/adhesin; Filamentous hemagglutinin; filamentous hemagglutinin/adhesin]
other gene names :
[fhaB; fhaB]
uniprot entry name :
FHAB_BORPE
purity :
72% pure by SDS-PAGE
form :
Supplied as a liquid, pH 8.8
concentration :
0.886 mg/ml; HA Activity: 0.78ug/HA Unit
storage stability :
Upon receipt store at -70 degree C. Avoid repeated freeze/thaw cycles. Shipping: Ships with Dry Ice.
tested application :
ELISA (EIA)
app notes :
Optimal conditions to be determined by end user.
other info1 :
Source: Bordetella Pertussis. Contaminants: Endotoxin 2.5EU/ug. Protein Type: Native. Biological Significance: Filamentous haemagglutinin adhesin (FHA) is an important virulence factor from Bordetella pertussis related to the adhesion and spread of the bacteria through the respiratory tract. Filamentous hemagglutinin is a 220 kDa protein associated with the bacterial surface, but also secreted in substantial amounts. Studies using FHA-deficient B. pertussis strains implicate this protein in tracheal colonization, cell adherence, and invasion of macrophages and epithelial cells by B. pertussis. FHA is a useful tool in immunoassays and whooping cough vaccination studies.
other info2 :
Biohazard: Use standard laboratory precautions when handling this material. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
products categories :
Infectious Disease; Native Protein
products description :
Filamentous Hemagglutinin purified from Bordetella Pertussis
ncbi acc num :
NP_880571.1
ncbi gb acc num :
NC_002929.2
ncbi mol weight :
220 kDa
ncbi pathways :
Pertussis Pathway (218102); Pertussis Pathway (218099)
uniprot summary :
Evidence for a role in host-cell binding and infection.