catalog number :
MBS535881
products full name :
NOV antibody
products short name :
NOV
products name syn :
Polyclonal NOV; Anti-NOV; Nephroblastoma Overexpressed gene; CCN3; IGFBP9; NovH
other names :
protein NOV homolog; Protein NOV homolog; protein NOV homolog; nephroblastoma overexpressed; CCN family member 3; Insulin-like growth factor-binding protein 9; IBP-9; IGF-binding protein 9; IGFBP-9; Nephroblastoma-overexpressed gene protein homolog
other gene names :
NOV; NOV; CCN3; NOVh; IBP-9; IGFBP9; IGFBP-9; CCN3; IGFBP9; NOVH; NovH; IBP-9; IGF-binding protein 9; IGFBP-9
uniprot entry name :
NOV_HUMAN
reactivity :
To be determined by end-user
form :
Lyophilized from PBS, pH 7.2.
storage stability :
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Inhibition, Western Blot (WB)
other info1 :
Biological Significance: NOV is a member of the CCN family of secreted cysteine rich regulatory proteins. The full length NOV protein contains four structural domains that confer distinct, and sometimes opposing, biological activities. Elevated expression of NOV is associated with certain tumors, including Wilm?s tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorgenicity and proliferation is correlated with decreased NOV expression.
other info2 :
Immunogen: NOV antibody was raised in rabbit using highly pure recombinant human NOV as the immunogen.
products categories :
Cytokines & Growth Factors; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal NOV antibody
ncbi gb acc num :
NM_002514.3
ncbi mol weight :
36.2 kDa (predicted detection band MW)
ncbi pathways :
Delta-Notch Signaling Pathway 198879
ncbi summary :
The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009]