product summary
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company name :
MyBioSource
product type :
antibody
product name :
Alpha 1 Antichymotrypsin antibody
catalog :
MBS535865
quantity :
1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS535865
products type :
Antibody
products full name :
Alpha 1 Antichymotrypsin antibody
products short name :
Alpha 1 Antichymotrypsin
products name syn :
Polyclonal Alpha 1 Antichymotrypsin; Anti-Alpha 1 Antichymotrypsin; A1-ACT; Alpha-1 Antichymotrypsin; A1ACT
other names :
alpha-1-antichymotrypsin; Alpha-1-antichymotrypsin; alpha-1-antichymotrypsin; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; Cell growth-inhibiting gene 24/25 protein; Serpin A3
other gene names :
SERPINA3; SERPINA3; ACT; AACT; GIG24; GIG25; AACT; ACT
uniprot entry name :
AACT_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Specific for Human Alpha-1-antichymotrypsin
sequence length :
423
specificity :
Alpha 1 Antichymotrypsin antibody was raised against Human Alpha-1-Antichymotrypsin
purity :
Affinity purified using solid phase Human Alpha-1-Antichymotrypsin
form :
0.2 mM filtered, in 10 mM Sodium Phosphate, 150mM Sodium Chloride, pH7.2 and 0.05% Sodium Azide as a preservative.
concentration :
2.04 mg/ml
storage stability :
Store at 4 degree C.
tested application :
User optimized
app notes :
The optimal working dilution should be determined by the end user
other info1 :
Source Note: Goat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian. Biological Significance: Alpha 1 antichymotrypsin is an alpha globulin glycoprotein that is a member of the serpin superfamily. It inhibits the activity of certain enzymes called proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving them into a different shape or conformation. This activity protects some tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes.
other info2 :
Immunogen: Alpha 1 Antichymotrypsin antibody was raised in goat using Human Alpha-1-Antichymotrypsin as the immunogen.
products categories :
Proteases, Inhibitors, Purified Polyclonal Antibodies
products description :
Affinity purified Goat polyclonal Alpha 1 Antichymotrypsin antibody
ncbi gi num :
50659080
ncbi acc num :
NP_001076.2
ncbi gb acc num :
NM_001085.4
uniprot acc num :
P01011
ncbi mol weight :
10,717 Da
ncbi pathways :
Selenium Pathway (198825)
ncbi summary :
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]
uniprot summary :
SERPINA3: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Belongs to the serpin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 14q32.1. Cellular Component: extracellular space; extracellular region; intracellular; nucleus. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; DNA binding. Biological Process: regulation of lipid metabolic process; maintenance of gastrointestinal epithelium; acute-phase response; inflammatory response
size1 :
1 mg
price1 :
300 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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