catalog number :
MBS535735
products full name :
LIX antibody
products short name :
LIX
products name syn :
Polyclonal LIX; Anti-LIX; ENA-78; CXCL5
other names :
LIX; C-X-C motif chemokine 5; C-X-C motif chemokine 5; chemokine (C-X-C motif) ligand 5; Cytokine LIX; Small-inducible cytokine B5
other gene names :
Cxcl5; Cxcl5; LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II; Scyb5
uniprot entry name :
CXCL5_MOUSE
reactivity :
To be determined by end-user
form :
Lyophilized from PBS, pH 7.2.
storage stability :
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Inhibition, Western Blot (WB)
other info1 :
Biological Significance: The Mouse homolog of ENA-78 is called LIX. LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ?ELR? motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors.
other info2 :
Immunogen: LIX antibody was raised in rabbit using highly pure recombinant murine LIX as the immunogen.
products categories :
Cytokines & Growth Factors; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal LIX antibody
ncbi acc num :
AAC52238.1
ncbi mol weight :
7.6 kDa (predicted detection band MW)
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway 1168363!!Chemokine Signaling Pathway 99271!!Chemokine Signaling Pathway 672435!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 1168361!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!G Alpha (i) Signalling Events Pathway 1168392!!GPCR Downstream Signaling Pathway 1168390!!GPCR Ligand Binding Pathway 1168360
ncbi summary :
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils and to have homeostatic and inflammatory functions. In mouse, deficiency of this gene is associated with increased lung inflammation that is neutrophil-dependent. [provided by RefSeq, May 2013]