catalog number :
MBS535724
products full name :
ICAM1 antibody
products short name :
ICAM1
products name syn :
Polyclonal ICAM1; Anti-ICAM1; Intercellular adhesion molecule 1; ICAM-1; ICAM 1; ICAM1; major group rhinovirus receptor; CD54 antigen
other names :
intercellular adhesion molecule 1; Intercellular adhesion molecule 1; intercellular adhesion molecule 1; intercellular adhesion molecule 1; Major group rhinovirus receptor; CD_antigen: CD54
products gene name :
ICAM1
other gene names :
ICAM1; ICAM1; BB2; CD54; P3.58; ICAM-1
uniprot entry name :
ICAM1_HUMAN
reactivity :
To be determined by end-user
specificity :
Human ICAM1
form :
Lyophilized from PBS, pH 7.2.
storage stability :
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Inhibition, Western Blot (WB)
app notes :
ELISA: 0.5-2 ug/ml. Inhibition: 8 ug/ml. WB: 0.1-0.2 ug/ml
other info1 :
Biological Significance: ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain. Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1.
other info2 :
Immunogen: ICAM1 antibody was raised in rabbit using highly pure recombinant human ICAM-1 as the immunogen.
products categories :
Immunology; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal ICAM1 antibody
ncbi gb acc num :
NM_000201.2
ncbi mol weight :
72-80 kDa (predicted detection band MW)
ncbi pathways :
Adaptive Immune System Pathway 366160!!African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Cytokine Signaling In Immune System Pathway 366171!!Epstein-Barr Virus Infection Pathway 585562!!Epstein-Barr Virus Infection Pathway 587115!!Extracellular Matrix Organization Pathway 576262!!Glucocorticoid Receptor Regulatory Network Pathway 138014
ncbi summary :
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]