catalog number :
MBS535723
products full name :
Galectin 3 antibody
products short name :
Galectin 3
products name syn :
Polyclonal Galectin 3; Anti-Galectin 3; Galectin -3; MAC2; L-29; Galectin 3; IgE-binding; Galectin-3; CPB-35
other names :
galectin-3; Galectin-3; galectin-3; lectin, galactoside-binding, soluble, 3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen
other gene names :
LGALS3; LGALS3; L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2; MAC2; Gal-3; CBP 35; GALBP
uniprot entry name :
LEG3_HUMAN
reactivity :
To be determined by end-user
specificity :
Human galectin 3
form :
Lyophilized from PBS, pH 7.2. Reconstitute in sterile water to a concentration of at least 0.1-1.0 mg/ml.
storage stability :
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Inhibition, Western Blot (WB)
other info1 :
Biological Significance: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 is normally expressed in epithelia of a variety of tissues, including colon and endometrium, and in various inflammatory cells, including macrophages.
other info2 :
Immunogen: Galectin 3 antibody was raised in rabbit using highly pure recombinant human galectin-3 as the immunogen.
products categories :
Nutrition & Metabolism; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal Galectin 3 antibody
ncbi acc num :
BAA22164.1
ncbi mol weight :
26.0 kDa (predicted detection band MW)
ncbi pathways :
AGE/RAGE Pathway 698754!!Advanced Glycosylation Endproduct Receptor Signaling Pathway 187092!!Hedgehog Signaling Events Mediated By Gli Proteins Pathway 137912!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!Spinal Cord Injury Pathway 739007
ncbi summary :
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]