This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
CD40L antibody
catalog :
MBS535692
quantity :
0.05 mg
price :
310 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
product information
catalog number :
MBS535692
products type :
Antibody
products full name :
CD40L antibody
products short name :
CD40L
products name syn :
Polyclonal CD40L; Anti-CD40L; CD40L; TRAP; CDL 40; CDL-40; TNFSF5; T-BAM; CD154; soluble CD40 Ligand; gp39
other names :
CD40 ligand; CD40 ligand; CD40 ligand; CD40 ligand; T-cell antigen Gp39; TNF-related activation protein; TRAP
products gene name :
CD40L
other gene names :
CD40LG; CD40LG; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40L; TNFSF5; TRAP; CD40-L; TRAP
uniprot entry name :
CD40L_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
To be determined by end-user
sequence length :
261
specificity :
Human CD40L
form :
Lyophilized from PBS, pH 7.2.
storage stability :
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Inhibition, Western Blot (WB)
other info1 :
Biological Significance: CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to "immunodeficiency with hyper-IgM", a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain.
other info2 :
Immunogen: CD40L antibody was raised in rabbit using highly pure recombinant human sCD40L as the immunogen.
products categories :
Immunology; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal CD40L antibody
ncbi gi num :
4557433
ncbi acc num :
NP_000065.1
ncbi gb acc num :
NM_000074.2
uniprot acc num :
P29965
ncbi mol weight :
16.3 kDa (predicted detection band MW)
ncbi pathways :
Adaptive Immune System Pathway 366160!!Allograft Rejection Pathway 920963!!Allograft Rejection Pathway 83123!!Allograft Rejection Pathway 535!!Asthma Pathway 83120!!Asthma Pathway 532!!Autoimmune Thyroid Disease Pathway 83121!!Autoimmune Thyroid Disease Pathway 533!!CD40/CD40L Signaling Pathway 138061!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993
ncbi summary :
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
310 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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