catalog number :
MBS535546
products full name :
OXER1 antibody
products short name :
[OXER1]
products name syn :
[Polyclonal OXER1; Anti-OXER1; 8Z; HM74-like Receptor; OXER 1; tg1019; HEOAD54; OXER -1; 11Z; OXER1; r527; 14Z-Eicosatetraenoic Acid Receptor; 5-oxo-6E]
other names :
[oxoeicosanoid receptor 1; Oxoeicosanoid receptor 1; oxoeicosanoid receptor 1; oxoeicosanoid (OXE) receptor 1; 5-oxo-ETE G-protein coupled receptor; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019]
products gene name :
[OXER1]
other gene names :
[OXER1; OXER1; GPCR; GPR170; TG1019; GPR170; TG1019]
uniprot entry name :
OXER1_HUMAN
purity :
OXER1 antibody was purified by affinity chromatography.
form :
Immunoaffinity purified liquid in PBS, with <0.15 NaN3.
concentration :
1.0 mg/ml
storage stability :
4 degree C short term, or aliquot and store undiluted at -20 degree C long term.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
IHC-P: 11 ug/ml
other info1 :
Biological Significance: Oxoeicosanoid receptor 1 is a protein that in humans is encoded by the OXER1 gene. This protein acts as a receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE). It Seems to be coupled to the Gi/Go, families of heteromeric G proteins. Leukotriene and related receptors act on peroxisome-proliferating receptors (PPARs) as well as the G-protein-coupled leukotriene receptors, and are important in inflammatory signaling pathways.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: synthetic 18 amino acid peptide from 1st extracellular domain of human OXER1.
products categories :
Signal Transduction
products description :
Rabbit polyclonal OXER1 antibody
ncbi acc num :
NP_683765.1
ncbi gb acc num :
NM_148962.4
ncbi mol weight :
45,811 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Eicosanoid Ligand-binding Receptors Pathway (106370); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
uniprot summary :
OXER1: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. Belongs to the G-protein coupled receptor 1 family. Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 2p21. Cellular Component: integral to membrane; plasma membrane. Molecular Function: G-protein coupled receptor activity; 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding. Biological Process: G-protein coupled receptor protein signaling pathway; regulation of cAMP biosynthetic process