catalog number :
MBS535481
products full name :
GPR44 antibody
products short name :
GPR44
products name syn :
Polyclonal GPR44; Anti-GPR44; hCRTH2; gpr44; GPR -44; DP2 prostaglandin receptor; GPR44; chemoattractant receptor-homologous molecule expressed on th2; GPR 44; crth2; G protein-coupled receptor 44; prostaglandin D(2) (PGD(2)) receptor
other names :
G protein-coupled receptor 44; Prostaglandin D2 receptor 2; prostaglandin D2 receptor 2; prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CD_antigen: CD294
products gene name :
GPR44
other gene names :
PTGDR2; PTGDR2; DP2; DL1R; CD294; CRTH2; GPR44; CRTH2; DL1R; GPR44
uniprot entry name :
PD2R2_HUMAN
reactivity :
To be determined by end-user
purity :
GPR44 antibody was purified by affinity chromatography.
form :
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.
concentration :
1.0 mg/ml
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -70 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
IHC-P: 15 ug/ml
other info1 :
Biological Significance: G protein-coupled receptors (GPCRs), comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. G protein-coupled receptors are found only in eukaryotes, including yeast, choanoflagellates, and animals. GPR44 has recently been found to belong to the prostanoid receptor family and named DP2, with this becoming the official IUPHAR nomenclature.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: GPR44 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
products categories :
Signal Transduction
products description :
Rabbit polyclonal GPR44 antibody
ncbi acc num :
AAH96841.1
ncbi mol weight :
43,268 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Eicosanoid Ligand-binding Receptors Pathway 106370!!G Alpha (i) Signalling Events Pathway 119550!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886!!Prostanoid Ligand Receptors Pathway 106371!!Signal Transduction Pathway 477114!!Signaling By GPCR Pathway 106356
ncbi summary :
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]