product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Histidine Decarboxylase antibody
catalog :
MBS535374
quantity :
0.05 mL
price :
865 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS535374
products type :
Antibody
products full name :
Histidine Decarboxylase antibody
products short name :
Histidine Decarboxylase
products name syn :
Polyclonal Histidine Decarboxylase; Anti-Histidine Decarboxylase; HDC
other names :
histidine decarboxylase isoform 1; Histidine decarboxylase; histidine decarboxylase; histidine decarboxylase
other gene names :
HDC; HDC; HDC
uniprot entry name :
DCHS_HUMAN
clonality :
Polyclonal
isotype :
IgG1
host :
Rabbit
reactivity :
Dog, Guinea Pig, Human, Mouse, Rat
sequence length :
662
specificity :
E Coli histidine decarboxylase
purity :
Whole antiserum
form :
Supplied as a lyophilized powder. Dissolve the antiserum in 50 - 100 ul distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.1% NaN3.
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze-thaw cycles.
tested application :
Immunofluorescence (IF)
app notes :
IF: 1:1,000-1:1,500
other info1 :
Biological Significance: Histidine decarboxylase (HDC) is the enzyme catalyzing the conversion of histidine into histamine. HDC can be found in the histamine secreting ECL cells of some species as well as in the mast cells.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Histidine decarboxylase antibody was raised in rabbit using recombinant histidine decarboxylase produced in E Coli as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Rabbit polyclonal Histidine Decarboxylase antibody
ncbi gi num :
92110055
ncbi acc num :
NP_002103.2
ncbi gb acc num :
NM_002112.3
uniprot acc num :
P19113
ncbi mol weight :
70,059 Da
ncbi pathways :
Biogenic Amine Synthesis Pathway (198793); Histidine Catabolism Pathway (106186); Histidine Metabolism Pathway (82958); Histidine Metabolism Pathway (324); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Histamine Biosynthesis Pathway (545324); Histamine Biosynthesis Pathway (138678)
ncbi summary :
This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010]
uniprot summary :
HDC: a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010]. Protein type: Lyase; EC 4.1.1.22; Amino Acid Metabolism - histidine. Chromosomal Location of Human Ortholog: 15q21.2. Cellular Component: cytosol. Molecular Function: pyridoxal phosphate binding; histidine decarboxylase activity. Biological Process: catecholamine biosynthetic process; histamine biosynthetic process; histidine metabolic process; histidine catabolic process. Disease: Gilles De La Tourette Syndrome
size1 :
0.05 mL
price1 :
865 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!