product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
CYP3A1 antibody
catalog :
MBS535337
quantity :
0.1 mL
price :
615 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
rat
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS535337
products type :
Antibody
products full name :
CYP3A1 antibody
products short name :
CYP3A1
products name syn :
Polyclonal CYP3A1; Anti-CYP3A1; Cytochrome P-450; Cytochrome P450 3A1; Cytochrome P 450; Rat CYP3A1; Cytochrome P450
other names :
Cytochrome P450 3A1; Cytochrome P450 3A1; cytochrome P450 3A1; cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1; CYPIIIA1; Cytochrome P450-PCN1
products gene name :
CYP3A1
other gene names :
Cyp3a23/3a1; Cyp3a1; CYP; RL33; cDEX; Cyp3a1; Cyp3a3; CYP3A23; Cyp3a-1
uniprot entry name :
CP3A1_RAT
clonality :
Polyclonal
host :
Rabbit
reactivity :
Rat
sequence length :
504
form :
Supplied as rabbit antiserum with no preservatives added.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
tested application :
Immunohistochemistry (IHC), Western Blot (WB)
other info1 :
Biological Significance: The cytochrome P450 superfamily (officially abbreviated as CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances such as drugs and other toxic chemicals. The CYP3A locus includes all the known members of the 3A subfamily of the cytochrome P450 superfamily of genes. These genes encode monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
other info2 :
Immunogen: CYP3A1 antibody was raised in rabbit using a synthetic peptide as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Rabbit polyclonal CYP3A1 antibody
ncbi gi num :
117153
ncbi acc num :
P04800.1
uniprot acc num :
P04800
ncbi mol weight :
57,918 Da
ncbi pathways :
Aflatoxin Activation And Detoxification Pathway (1178289); Biological Oxidations Pathway (1178258); Chemical Carcinogenesis Pathway (673233); Chemical Carcinogenesis Pathway (673237); Cytochrome P450 - Arranged By Substrate Type Pathway (1178260); Linoleic Acid Metabolism Pathway (83384); Linoleic Acid Metabolism Pathway (367); Metabolic Pathways (132933); Metabolism Pathway (1178040); Miscellaneous Substrates Pathway (1178269)
ncbi summary :
steroid-inducible member of p450 subfamily 3A; induced by pregnenolone 16 alpha-carbonitrile, dexamethasone (DEX), phenobarbital (PB) and triacetyloleandomycin [RGD, Feb 2006]
uniprot summary :
CYP3A5: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Lipid Metabolism - linoleic acid; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - drug metabolism - other enzymes; Cofactor and Vitamin Metabolism - retinol; EC 1.14.14.1; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450. Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle. Molecular Function: iron ion binding; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; demethylase activity; testosterone 6-beta-hydroxylase activity. Biological Process: response to drug; response to metal ion; response to cadmium ion; response to glucocorticoid stimulus; drug metabolic process; response to nutrient; aging
size1 :
0.1 mL
price1 :
615 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!