Collagen Type VI antibody | MyBioSource MBS535250 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Collagen Type VI antibody

catalog :

MBS535250

quantity :

0.1 mg

price :

340 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS535250

products type :

Antibody

products full name :

Collagen Type VI antibody

products short name :

[Collagen Type VI]

products name syn :

[Polyclonal Collagen Type VI; Anti-Collagen Type VI; CollagenVI; Human mRNA for collagen VI alpha 1 C terminal globular domain]

other names :

[collagen alpha-6(VI) chain; Collagen alpha-6(VI) chain; collagen alpha-6(VI) chain; collagen, type VI, alpha 6]

other gene names :

[COL6A6; COL6A6]

uniprot entry name :

CO6A6_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Reacts with most mammalian Type VI collagens. Less than 1% cross reactivity with Type I, II, III, IV and V collagens

sequence length :

2263

specificity :

Bovine/Human collagen VI

purity :

Collagen Type VI antibody was purified by affinity chromatography.

form :

Supplied in 125mM Sodium Borate, pH 8.0, with 75mM Sodium Chloride, 5mM EDTA and 0.01% Sodium Azide

concentration :

1.0 mg/ml by UV absorbance at 280 nm

storage stability :

Store at 4°C as an undiluted liquid. For extended storage, mix with an equal volume of glycerol and store at -20°C or below. Avoid freeze thaw cycles.

tested application :

ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)

app notes :

ELISA: 1:5,000-1:50,000. Western Blot: 1:1,000-1:10,000. IP: 1:100. IHC: 1:50-1:200

image1 heading :

Immunohistochemistry IHC

other info1 :

Immunogen: Collagen type VI from human and bovine placenta. Biological Significance: Collagen is a group of naturally occurring proteins found, in nature, exclusively in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. Collagen alpha-1(VI) chain is a protein that in humans is encoded by the COL6A1 gene. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. Bioactivity: Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues

other info2 :

Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

products categories :

Cancer; Purified Polyclonal Antibodies

products description :

Affinity purified Rabbit polyclonal Collagen Type VI antibody

products references :

Differential and restricted expression of novel collagen VI chains in mouse; Sudheer Kumar Gara, Paolo Grumati, Stefano Squarzoni, Patrizia Sabatelli, Anna Urciuolo, Paolo Bonaldo, Mats Paulsson, Raimund Wagener (Matrix Biology: Volume: 30 Issue: 4 Page: 248257 DOI: 10.1016/j.matbio.2011.03.006)

ncbi gi num :

156616290

ncbi acc num :

NP_001096078.1

ncbi gb acc num :

NM_001102608.1

uniprot acc num :

A6NMZ7

ncbi pathways :

Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Axon Guidance Pathway (105688); Collagen Biosynthesis And Modifying Enzymes Pathway (645289); Collagen Formation Pathway (645288); Developmental Biology Pathway (477129); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (576262); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478)

uniprot summary :

COL6A6: Collagen VI acts as a cell-binding protein. Belongs to the type VI collagen family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3q22.1. Cellular Component: proteinaceous extracellular matrix; collagen; extracellular region. Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; cell adhesion

size1 :

0.1 mg

price1 :

340 USD

more info or order :

MyBioSource product webpage