product summary
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company name :
MyBioSource
product type :
antibody
product name :
Kallikrein antibody
catalog :
MBS535095
quantity :
1 mL
price :
450 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS535095
products type :
Antibody
products full name :
Kallikrein antibody
products short name :
Kallikrein
products name syn :
Polyclonal Kallikrein; Anti-Kallikrein
other names :
kallikrein; Kallikrein-1; kallikrein-1; kallikrein 1; Kidney/pancreas/salivary gland kallikrein; Tissue kallikrein
other gene names :
KLK1; KLK1; hK1; KLKR; Klk6
uniprot entry name :
KLK1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
262
form :
Purified IgG fraction supplied in PBS with 0.05% NaN3.
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Biological Significance: Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. The novel KLK gene, KLK-L2 (also known as KLK5) is expressed in breast, brain, and testis and is up-regulated by estrogens and progestins.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Kallikrein antibody was raised in rabbit using human kallikrein as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Rabbit polyclonal Kallikrein antibody
ncbi gi num :
186653
ncbi acc num :
AAA36136.1
uniprot acc num :
P06870
ncbi mol weight :
23,835 Da
ncbi pathways :
Blood Clotting Cascade Pathway (198840); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213307); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213276); Metabolism Of Proteins Pathway (106230); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (105908)
ncbi summary :
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008]
uniprot summary :
KLK1: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.21.35; Protease. Chromosomal Location of Human Ortholog: 19q13.3. Cellular Component: nucleus. Molecular Function: serine-type endopeptidase activity. Biological Process: proteolysis. Disease: Kallikrein, Decreased Urinary Activity Of
size1 :
1 mL
price1 :
450 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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