product summary
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company name :
MyBioSource
product type :
antibody
product name :
CYP1A1 antibody
catalog :
MBS535086
quantity :
0.1 ml
price :
615 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS535086
products type :
Antibody
products full name :
CYP1A1 antibody
products short name :
CYP1A1
products name syn :
Polyclonal CYP1A1; Anti-CYP1A1; Cytochrome P 450; Cytochrome P450; Cytochrome P-450; Cytochrome P450 1A1
other names :
cytochrome P450 1A1; Cytochrome P450 1A1; cytochrome P450 1A1; cytochrome P450, family 1, subfamily A, polypeptide 1; CYPIA1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1
products gene name :
CYP1A1
other gene names :
CYP1A1; CYP1A1; AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX
uniprot entry name :
CP1A1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
To be determined by end-user
sequence length :
512
form :
Neat serum with no preservatives.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
tested application :
Immunohistochemistry (IHC), Western Blot (WB)
other info1 :
Biological Significance: The cytochrome P450 superfamily (officially abbreviated as CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances such as drugs and other toxic chemicals. CYP1A1 is involved in phase I xenobiotic and drug metabolism (one substrate of it is theophylline). It is inhibited by fluoroquinolones and macrolides and induced by aromatic hydrocarbons.
other info2 :
Immunogen: CYP1A1 antibody was raised in rabbit using a synthetic peptide as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Rabbit polyclonal CYP1A1 antibody
ncbi gi num :
4503199
ncbi acc num :
NP_000490
ncbi gb acc num :
NM_000499.3
uniprot acc num :
P04798
ncbi mol weight :
18,441 Da
ncbi pathways :
AhR Pathway 755436!!Arachidonic Acid Metabolism Pathway 685553!!Benzo(a)pyrene Metabolism Pathway 198911!!Biological Oxidations Pathway 105698!!Chemical Carcinogenesis Pathway 673221!!Chemical Carcinogenesis Pathway 673237!!Cytochrome P450 - Arranged By Substrate Type Pathway 105700!!Estrogen Metabolism Pathway 198898!!Fatty Acid Omega Oxidation Pathway 198915!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977
ncbi summary :
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]
size :
0.1 ml
price :
615 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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