catalog number :
MBS535071
products full name :
Leptin antibody
products short name :
Leptin
products name syn :
Polyclonal Leptin; Anti-Leptin; OB; Obesity
other names :
leptin; leptin; leptin<
other gene names :
lep; ob; xlep
reactivity :
To be determined by end-user
specificity :
Human leptin
form :
Lyophilized from PBS, pH 7.2. Reconstitute with sterile water to a concentration of 0.1 - 1.0 mg/ml.
storage stability :
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Inhibition, Western Blot (WB)
other info1 :
Biological Significance: Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models.
other info2 :
Immunogen: Leptin antibody was raised in rabbit using highly pure recombinant human leptin as the immunogen.
products categories :
Hormones & Steroids; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal Leptin antibody
ncbi acc num :
NP_001089183.1
ncbi gb acc num :
NM_001095714.1
ncbi mol weight :
16.2 kDa (predicted detection band MW)
ncbi pathways :
Adipocytokine Signaling Pathway 119298!!Adipocytokine Signaling Pathway 505!!Cytokine-cytokine Receptor Interaction Pathway 119282!!Cytokine-cytokine Receptor Interaction Pathway 460!!Jak-STAT Signaling Pathway 84661!!Jak-STAT Signaling Pathway 488!!Neuroactive Ligand-receptor Interaction Pathway 119283!!Neuroactive Ligand-receptor Interaction Pathway 462