catalog number :
MBS534936
products full name :
Eotaxin 3 antibody (biotin)
products short name :
Eotaxin 3
products name syn :
Polyclonal Eotaxin 3; Anti-Eotaxin 3; CCL26; Eotaxin-3
other names :
eotaxin-3; C-C motif chemokine 26; C-C motif chemokine 26; chemokine (C-C motif) ligand 26; CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1
other gene names :
CCL26; CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha; SCYA26; MIP-4-alpha; TSC-1
uniprot entry name :
CCL26_HUMAN
reactivity :
To be determined by end-user
specificity :
Human eotaxin 3
form :
Lyophilized from PBS, pH 7.2. Reconstitute to a concentration of 50 ug/ml with sterile PBS solution containing 0.1 %BSA.
storage stability :
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA: 0.25-1 ug/ml. WB: 0.1-0.2 ug/ml
other info1 :
Biological Significance: Eotaxin-3 is a CC chemokine that signals through the CCR3 receptor. It is produced by endothelial cells stimulated with IL4 or IL13. Eotaxin-3 selectively targets cells expressing CCR3, including eosinophils, basophils, T cells and monocytes. Eotaxin-3 has similar activity to Eotaxin and Eotaxin-2, but the three Eotaxins share only a low degree of sequence homology.
other info2 :
Tag/Conjugate: Biotin. Immunogen: Eotaxin 3 antibody (biotin) was raised in goat using highly pure recombinant human eotaxin-3 as the immunogen.
products categories :
Cytokines & Growth Factors; Conjugated Polyclonal Antibodies
products description :
Goat polyclonal Eotaxin 3 antibody (biotin)
ncbi acc num :
BAA36704.1
ncbi mol weight :
8.4 kDa (predicted detection band MW)
ncbi pathways :
Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!IL4-mediated Signaling Events Pathway 137933
ncbi summary :
This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]