product summary
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company name :
MyBioSource
product type :
antibody
product name :
PTH antibody
catalog :
MBS534917
quantity :
1 mL
price :
170 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
mouse
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS534917
products type :
Antibody
products full name :
PTH antibody
products short name :
[PTH]
products name syn :
[Polyclonal PTH; Anti-PTH; N terminal PTH; Parathyroid Hormone]
other names :
[parathyroid hormone; Parathyroid hormone; parathyroid hormone; parathyroid hormone]
products gene name :
[PTH]
other gene names :
[Pth; Pth; Pthp; PTH]
uniprot entry name :
Q9Z0L6_MOUSE
clonality :
Polyclonal
host :
Goat
reactivity :
N-Terminal PTH 100%
sequence length :
115
specificity :
Human
form :
Defibrinated plasma with no preservatives.
concentration :
~7,000 tests/ml in 125I RIA
storage stability :
Ships on blue ice. Upon receipt, store at -20°C.
tested application :
User optimized
other info2 :
Immunogen: PTH, human
products categories :
Hormones & Steroids
products description :
Parathyroid hormone (PTH), parathormone or parathyrin, is secreted by the parathyroid glands as a polypeptide containing 84 amino acids. PTH acts to increase the concentration of calcium in the blood by acting upon parathyroid hormone receptor in three parts of the body. PTH half-life is approximately 4 minutes.
ncbi gi num :
10181174
ncbi acc num :
NP_065648.1
ncbi gb acc num :
NM_020623.2
uniprot acc num :
Q9Z0L6
ncbi pathways :
Class B/2 (Secretin Family Receptors) Pathway (1168386); Endochondral Ossification Pathway (198336); G Alpha (s) Signalling Events Pathway (1168391); GPCR Downstream Signaling Pathway (1168390); GPCR Ligand Binding Pathway (1168360); Osteoblast Pathway (198413); Signal Transduction Pathway (1168181); Signaling By GPCR Pathway (1168359)
uniprot summary :
PTH: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Belongs to the parathyroid hormone family. Protein type: Secreted; Hormone; Secreted, signal peptide; Apoptosis. Cellular Component: extracellular space; cell; intracellular. Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; type 1 parathyroid hormone receptor binding; parathyroid hormone receptor binding; peptide hormone receptor binding; hormone activity. Biological Process: transcription from RNA polymerase II promoter; positive regulation of signal transduction; positive regulation of glycogen biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of bone mineralization; G-protein signaling, adenylate cyclase activating pathway; Rho protein signal transduction; positive regulation of ossification; cellular calcium ion homeostasis; positive regulation of glucose import; cell-cell signaling; regulation of gene expression; positive regulation of cAMP biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; skeletal development; bone resorption. Disease: Hypoparathyroidism, Familial Isolated
size1 :
1 mL
price1 :
170 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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