catalog number :
MBS534885
products full name :
PPAR Delta antibody
products short name :
PPAR Delta
products name syn :
Polyclonal PPAR Delta; Anti-PPAR Delta
other names :
peroxisome proliferator-activated receptor delta isoform 3; Peroxisome proliferator-activated receptor delta; peroxisome proliferator-activated receptor delta; peroxisome proliferator-activated receptor delta; NUCI; Nuclear hormone receptor 1; NUC1; Nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta; PPAR-beta
products gene name :
PPAR Delta
other gene names :
PPARD; PPARD; FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB; NR1C2; PPARB; PPAR-delta; NUC1; PPAR-beta
uniprot entry name :
PPARD_HUMAN
purity :
PPAR Delta antibody was purified by affinity chromatography.
form :
Epitope affinity purifioed and supplied in PBS with 1 mg/ml BSA and 0.05% NaN3.
concentration :
1.0 mg/ml
storage stability :
Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin, Western Blot (WB)
app notes :
IF: 1:100. IHC-F: 1:200. WB: 1:500
other info1 :
Biological Significance: Peroxisome proliferator activated receptors (PPARs) are members of the nuclear hormone receptor family. Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: PPAR Delta antibody was raised in rabbit using a synthetic peptide corresponding to residues M(1) E Q P Q E E T P E A R E E(14) C of mouse PPAR delta.
products categories :
DNA & RNA
products description :
Rabbit polyclonal PPAR Delta antibody
ncbi acc num :
NP_001165290.1
ncbi gb acc num :
NM_001171819.1
ncbi mol weight :
38,855 Da
ncbi pathways :
Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Adipogenesis Pathway 198832!!Energy Metabolism Pathway 198907!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Gene Expression Pathway 105937!!Generic Transcription Pathway 105938!!Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway 106108!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976
ncbi summary :
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]