catalog number :
MBS534883
products full name :
CKBB antibody
products short name :
CKBB
products name syn :
Polyclonal CKBB; Anti-CKBB; Creatine Kinase BB Isoenzyme; CK BB; CKBB
other names :
creatine kinase B-type; Creatine kinase B-type; creatine kinase B-type; creatine kinase, brain; B-CK; Creatine kinase B chain
products gene name :
CKBB
other gene names :
CKB; CKB; BCK; B-CK; CKBB; HEL-211; HEL-S-29; CKBB
uniprot entry name :
KCRB_HUMAN
form :
Neat serum with 0.1% NaN3.
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Biological Significance: In the cells, the "cytosolic" creatine kinase (CK) enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes: B on 14q32 and M on 19q13. In addition to those three cytosolic CK isoforms, there are two mitochondrial creatine kinase isoenzymes, the ubiquitous and sarcomeric form.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: CKBB antibody was raised in goat using purified human brain CKBB as the immunogen.
products categories :
Cardiac Markers
products description :
Goat polyclonal CKBB antibody
ncbi acc num :
NP_001814.2
ncbi gb acc num :
NM_001823.4
ncbi mol weight :
42,644 Da
ncbi pathways :
Arginine And Proline Metabolism Pathway 82957!!Arginine And Proline Metabolism Pathway 323!!Creatine Metabolism Pathway 106192!!Creatine Pathway 413359!!Creatine Pathway 468234!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Amino Acids And Derivatives Pathway 106169!!Urea Cycle And Metabolism Of Amino Groups Pathway 198758!!Creatine-phosphate Biosynthesis Pathway 545319
ncbi summary :
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]