catalog number :
MBS534836
products full name :
SGLT1 antibody
products short name :
SGLT1
products name syn :
Polyclonal SGLT1; Anti-SGLT1; SGLT 1; Sodium Glucose Transporter-1; SGLT1; SGLT -1; SGLT-1
other names :
sodium/glucose cotransporter 1 isoform 1; Sodium/glucose cotransporter 1; sodium/glucose cotransporter 1; solute carrier family 5 (sodium/glucose cotransporter), member 1; High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1
products gene name :
SGLT1
other gene names :
SLC5A1; SLC5A1; NAGT; SGLT1; D22S675; NAGT; SGLT1; Na(+)/glucose cotransporter 1
uniprot entry name :
SC5A1_HUMAN
reactivity :
Pig, Avian, Dog, Cat, Rabbit, Rat, Reptilia
purity :
SGLT1 antibody was purified by affinity chromatography.
form :
Supplied as a lyophilized powder containing 0.05% NaN3. Reconstitute in 100 ul of water.
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA: 0.5-1 ug/ml. WB: 1-10 ug/ml
other info1 :
Biological Significance: Sodium glucose co transporters (SGLT), are active in the reabsorption of glucose in the proximal tubules of the kidneys. In the kidney, SGLT1 is expressed in proximal tubule Sq1 segments. SGLT1/NAGT or SLC5A1/NAGT (rat/mouse 665 aa; human 664 aa, chromosome 22q13.1, ~75 kDa) is a high affinity, Na+-coupled, intestinal transporter responsible for active glucose transport across the brush border membrane.
other info2 :
Immunogen: SGLT1 antibody was raised in rabbit using a 19 amino acid peptide sequence of mouse/rabbit SGLT-1 as the immunogen.
products categories :
Nutrition & Metabolism; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal SGLT1 antibody
ncbi acc num :
NP_000334.1
ncbi gb acc num :
NM_000343.3
ncbi mol weight :
60,097 Da
ncbi pathways :
Bile Secretion Pathway 193146!!Bile Secretion Pathway 193095!!Carbohydrate Digestion And Absorption Pathway 170720!!Carbohydrate Digestion And Absorption Pathway 170654!!Hexose Transport Pathway 106198!!Inositol Transporters Pathway 119575!!Metabolism Pathway 477135!!Metabolism Of Carbohydrates Pathway 106196!!Mineral Absorption Pathway 212237!!Mineral Absorption Pathway 212220
ncbi summary :
This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]