antibody

PPAR alpha antibody

MBS534805

0.1 ml

745 USD

polyclonal

rabbit

nonconjugated

western blot, immunocytochemistry, immunoprecipitation

Antibody

PPAR alpha antibody

PPAR alpha

Polyclonal PPAR alpha; Anti-PPAR alpha

peroxisome proliferator-activated receptor alpha; Peroxisome proliferator-activated receptor alpha; peroxisome proliferator-activated receptor alpha; peroxisome proliferator-activated receptor alpha; Nuclear receptor subfamily 1 group C member 1

PPAR alpha

PPARA; PPARA; PPAR; NR1C1; hPPAR; PPARalpha; NR1C1; PPAR; PPAR-alpha

PPARA_HUMAN

Polyclonal

IgG

Rabbit

To be determined by end user

468

Murine

PPAR Alpha antibody was purified by affinity chromatography.

Purified IgG supplied in PBS with 1 mg/ml BSA and 0.05% NaN3.

1.0 mg/ml

Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.

Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)

IF: 1:100. WB: 1 ug/ml

Biological Significance: Peroxisome proliferator activated receptors (PPARs) are members of the nuclear hormone receptor family. Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding

Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: PPAR Alpha antibody was raised in rabbit using a synthetic peptide corresponding to residues M(1) V D T E S P I C P L S P L E A D D(18) C of mouse PPAR alpha.

Cancer

Rabbit polyclonal PPAR alpha antibody

The Glucagon Receptor Is Required for the Adaptive Metabolic Response to Fasting; Christine Longuet, Elaine M. Sinclair, Adriano Maida, Laurie L. Baggio, Marlena Maziarz, Maureen J. Charron, Daniel J. Drucker (Cell Metabolism: Volume: 8 Issue: 5 Page: 359-371 DOI: 10.1016/j.cmet.2008.09.008)

50348666

NP_001001928.1

NM_001001928.2

Q07869

18,942 Da

Activation Of Gene Expression By SREBF (SREBP) Pathway 685552!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Adipogenesis Pathway 198832!!BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway 477138!!Circadian Clock Pathway 187173!!Developmental Biology Pathway 477129!!Energy Metabolism Pathway 198907!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Gene Expression Pathway 105937

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]

0.1 ml

745 USD