This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Ubiquitin antibody
catalog :
MBS534788
quantity :
0.2 ml
price :
215 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS534788
products type :
Antibody
products full name :
Ubiquitin antibody
products short name :
Ubiquitin
products name syn :
Polyclonal Ubiquitin; Anti-Ubiquitin; UB
other names :
ubiquitin; Ubiquitin-40S ribosomal protein S27a; ubiquitin-40S ribosomal protein S27a; ribosomal protein S27a; Ubiquitin carboxyl extension protein 80
other gene names :
RPS27A; RPS27A; UBC; S27A; CEP80; UBA80; HEL112; UBCEP1; UBCEP80; UBA80; UBCEP1
uniprot entry name :
RS27A_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
To be determined by end-user
sequence length :
156
specificity :
Human ubiquitin
form :
Neat serum containing 0.01% Thimerosal as a preservative
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
ELISA: >1:5,000. WB: >1:1,000
other info1 :
Biological Significance: Ubiquitin is a small regulatory protein that has been found in almost all tissues (ubiquitously) of eukaryotic organisms. Among other functions, it directs proteins recycling. Ubiquitin binds to proteins and labels them for destruction. The ubiquitin tag directs proteins to the proteasome, which is a large protein complex in the cell that degrades and recycles unneeded proteins. This discovery won the Nobel Prize for chemistry in 2004.
other info2 :
Immunogen: Ubiquitin antibody was raised in rabbit using human ubiquitin as the immunogen.
products categories :
Protein Modification & Stress Response
products description :
Rabbit polyclonal Ubiquitin antibody
ncbi gi num :
37571
ncbi acc num :
CAA44911.1
uniprot acc num :
P62979
ncbi mol weight :
17,965 Da
ncbi pathways :
APC-Cdc20 Mediated Degradation Of Nek2A Pathway 1127551!!APC/C-mediated Degradation Of Cell Cycle Proteins Pathway 105825!!APC/C:Cdc20 Mediated Degradation Of Cyclin B Pathway 105832!!APC/C:Cdc20 Mediated Degradation Of Securin Pathway 105833!!APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway 105831!!APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway 105835!!APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway 1127549!!AUF1 (hnRNP D0) Destabilizes MRNA Pathway 187212!!Activated NOTCH1 Transmits Signal To The Nucleus Pathway 576270!!Activated NOTCH1 Transmits Signal To The Nucleus Pathway 1168352
ncbi summary :
Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.[provided by RefSeq, Sep 2008]
size :
0.2 ml
price :
215 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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