product summary
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company name :
MyBioSource
product type :
antibody
product name :
CYP2C11 antibody
catalog :
MBS534729
quantity :
0.1 mL
price :
685 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, ELISA, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS534729
products type :
Antibody
products full name :
CYP2C11 antibody
products short name :
CYP2C11
products name syn :
Polyclonal CYP2C11; Anti-CYP2C11; Cytochrome P450 2C11; Cytochrome P 450; Cytochrome P450; Cytochrome P-450
other names :
cytochrome P450 2C11; Cytochrome P450 2C11; cytochrome P450 2C11; cytochrome P450, subfamily 2, polypeptide 11; CYPIIC11; Cytochrome P-450(M-1); Cytochrome P450-UT-2; Cytochrome P450-UT-A; Cytochrome P450H
products gene name :
CYP2C11
other gene names :
Cyp2c11; Cyp2c11; Cyp2c; CYP2CII; Cyp2c; Cyp2c-11
uniprot entry name :
CP2CB_RAT
clonality :
Polyclonal
isotype :
IgG1
host :
Rabbit
reactivity :
Human, Rat
sequence length :
500
form :
Liquid in PBS with 0.05% sodium azide as preservative.
concentration :
1.0mg/ml
storage stability :
Sstore at -20 degree C. Avoid repeated freeze/thaw cycles. Shipping: 4 degree C only
tested application :
Western Blot (WB), Immunocytochemistry (ICC), ELISA
other info1 :
Biological Significance: The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. EET?s are converted from AA by the 2C11 family of P450?s whose expression is induced by testosterone and is therefore not generally found in females.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Synthetic peptides
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Rabbit polyclonal CYP2C11 antibody
ncbi gi num :
166091465
ncbi acc num :
NP_062057.2
ncbi gb acc num :
NM_019184.2
uniprot acc num :
P08683
ncbi pathways :
Arachidonate Epoxygenase Epoxide Hydrolase Pathway (219791); Arachidonic Acid Metabolism Pathway (83383); Arachidonic Acid Metabolism Pathway (366); Biological Oxidations Pathway (1178258); Chemical Carcinogenesis Pathway (673233); Chemical Carcinogenesis Pathway (673237); Cytochrome P450 - Arranged By Substrate Type Pathway (1178260); Inflammatory Mediator Regulation Of TRP Channels Pathway (948290); Inflammatory Mediator Regulation Of TRP Channels Pathway (948307); Linoleic Acid Metabolism Pathway (83384)
ncbi summary :
most abundant member of the p450 xenobiotic-inducible superfamily in non-stimulated liver; metabolizes xenobiotics and testosterone [RGD, Feb 2006]
uniprot summary :
CYP2C9: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S- warfarin, diclofenac, phenytoin, tolbutamide and losartan. Belongs to the cytochrome P450 family. Protein type: Xenobiotic Metabolism - drug metabolism - cytochrome P450; Secondary Metabolites Metabolism - limonene and pinene degradation; EC 1.14.14.1; Lipid Metabolism - linoleic acid; Cofactor and Vitamin Metabolism - retinol; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450; Lipid Metabolism - arachidonic acid. Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; cytoplasm. Molecular Function: iron ion binding; testosterone 16-alpha-hydroxylase activity; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; arachidonic acid epoxygenase activity; oxygen binding. Biological Process: xenobiotic metabolic process; exogenous drug catabolic process; epoxygenase P450 pathway
size1 :
0.1 mL
price1 :
685 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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