This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
UCP2 antibody
catalog :
MBS534655
quantity :
0.1 mg
price :
705 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
product information
catalog number :
MBS534655
products type :
Antibody
products full name :
UCP2 antibody
products short name :
UCP2
products name syn :
Polyclonal UCP2; Anti-UCP2; UCP2; UCP 2; UCP-2; UCP -2; Uncoupling Protein 2
other names :
uncoupling protein 2; Mitochondrial uncoupling protein 2; mitochondrial uncoupling protein 2; uncoupling protein 2 (mitochondrial, proton carrier); Solute carrier family 25 member 8; UCPH
products gene name :
UCP2
other gene names :
UCP2; UCP2; UCPH; BMIQ4; SLC25A8; SLC25A8; UCP 2
uniprot entry name :
UCP2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
To be determined by end-user
sequence length :
309
specificity :
Murine
purity :
UCP2 antibody was purified by affinity chromatography.
form :
Affinity purified antibody lyophilized from PBS with 0.1% BSA. Reconstitute in PBS to a concentraiton of 1 mg/ml.
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
ELISA: 1:10,000-1:100,000. IF: 2-20 ug/ml. WB: 1-10 ug/ml
other info1 :
Biological Significance: Uncoupling proteins (UCP1-5) are a family of mitochondria transport proteins that play a critical role in thermoregulatory heat production and maintenance of basal metabolic rate. UCP3 is predicted to contain 6 transmembrane domains. The UCP3S lacks the 6th transmembrane domain and it is only 275 aa long. Mouse/rat UCP2 is A 309 AA (human 309 aa chromosome 7; ~95% homology) mitochondrial uncoupling protein. UCP2 has wide tissue distribution in mouse tissues (brain, kidney, liver, brown adipose tissue, heart, and muscle). UCP2 may play a critical role in energy balance, body weight, and thermoregulation.
other info2 :
Immunogen: UCP2 antibody was raised in rabbit using a 14 amino acid peptide from mouse UCP2 as the immunogen.
products categories :
Nutrition & Metabolism; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal UCP2 antibody
ncbi gi num :
3176029
ncbi acc num :
CAA11402.1
uniprot acc num :
P55851
ncbi mol weight :
33,229 Da
ncbi pathways :
Electron Transport Chain Pathway 198860!!Energy Metabolism Pathway 198907!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!Metabolism Pathway 477135!!Mitochondrial Uncoupling Proteins Pathway 160963!!Respiratory Electron Transport, ATP Synthesis By Chemiosmotic Coupling, And Heat Production By Uncoupling Proteins. Pathway 105921!!The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway 477137!!The Fatty Acid Cycling Model Pathway 160964!!The Proton Buffering Model Pathway 160965
ncbi summary :
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
705 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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