catalog number :
MBS534625
products full name :
GLUT8 antibody
products short name :
GLUT8
products name syn :
Polyclonal GLUT8; Anti-GLUT8; GLUT 8; GLUT -8; GLUT8; Glucose Transporter 8; GLUT-8
other names :
glucose transporter 8; Solute carrier family 2, facilitated glucose transporter member 8; solute carrier family 2, facilitated glucose transporter member 8; solute carrier family 2 (facilitated glucose transporter), member 8; Glucose transporter type 8; GLUT-8; Glucose transporter type X1
products gene name :
GLUT8
other gene names :
SLC2A8; SLC2A8; GLUT8; GLUTX1; GLUT8; GLUTX1; GLUT-8
uniprot entry name :
GTR8_HUMAN
purity :
GLUT8 antibody was purified by affinity chromatography.
form :
Lyophilized from PBS with 0.1% BSA. Reconstitute in PBS to a concentration of 1 mg/ml.
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA: 0.5-1 ug/ml. WB: 1-10 ug/ml
other info1 :
Biological Significance: Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Glut isoforms differ in their tissue expression, substrate specificity and kinetic characteristics. Glut-8 (mouse 477-aa) is found in adult testis and placenta.
other info2 :
Immunogen: GLUT8 antibody was raised in rabbit using an 11 amino acid peptide from mouse Glut-6 as the immunogen.
products categories :
Cancer; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal GLUT8 antibody
ncbi acc num :
CAB89809.1
ncbi mol weight :
50,819 Da
ncbi pathways :
Facilitative Na+-independent Glucose Transporters Pathway (119572); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (119571)
ncbi summary :
This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
uniprot summary :
SLC2A8: Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. Protein type: Transporter; Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 9q33.3. Cellular Component: synaptic vesicle; cytoplasmic vesicle membrane; lysosomal membrane; integral to plasma membrane; plasma membrane. Molecular Function: glucose transmembrane transporter activity; glucose binding. Biological Process: male meiosis I; carbohydrate metabolic process; insulin receptor signaling pathway; response to hypoxia; glucose transport; transmembrane transport