catalog number :
MBS534576
products full name :
IFN alpha antibody
products short name :
IFN alpha
products name syn :
Polyclonal IFN alpha; Anti-IFN alpha; Interferon alpha
other names :
interferon-alpha; Interferon alpha-8; interferon alpha-8; interferon, alpha 8; Interferon alpha-B; LeIF B; Interferon alpha-B2
products gene name :
IFN alpha
other gene names :
IFNA8; IFNA8; IFN-alphaB; IFN-alpha-8; LeIF B
uniprot entry name :
IFNA8_HUMAN
form :
Neat Serum with no preservatives.
concentration :
>20,000 Neutralization Units per vial; 0.1ml per vial
storage stability :
Aliquot and store at -70 degree C or lower. Avoid repeated freeze/thaw cycles
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Neutralization
other info1 :
Biological Significance: Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. Bioactivity: In an antiviral assay for interferon, about 5 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%
other info2 :
Immunogen: IFN alpha antibody was raised in rabbit using mouse interferon alpha as the immunogen.
products categories :
Immunology
products description :
Rabbit polyclonal IFN alpha antibody
ncbi acc num :
AAA52716.1
ncbi mol weight :
21,989 Da
ncbi pathways :
Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Cytosolic DNA-sensing Pathway (125137); Cytosolic DNA-sensing Pathway (124833); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (187196); Hemostasis Pathway (106028); Hepatitis B Pathway (694606)
uniprot summary :
IFNA8: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family. Protein type: Secreted, signal peptide; Secreted; Cytokine. Chromosomal Location of Human Ortholog: 9p22. Cellular Component: extracellular space; extracellular region. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding; cytokine activity. Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; B cell differentiation; natural killer cell activation during immune response; innate immune response; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein