This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Dopamine Transporter antibody
catalog :
MBS534567
quantity :
0.1 mg
price :
655 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, dog
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS534567
products type :
Antibody
products full name :
Dopamine Transporter antibody
products short name :
Dopamine Transporter
products name syn :
Polyclonal Dopamine Transporter; Anti-Dopamine Transporter
other names :
dopamine transporter; Sodium-dependent dopamine transporter; sodium-dependent dopamine transporter; solute carrier family 6 (neurotransmitter transporter), member 3; Solute carrier family 6 member 3
other gene names :
SLC6A3; SLC6A3; DAT; DAT1; PKDYS; DAT1; DA transporter; DAT
uniprot entry name :
SC6A3_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Dog, Mouse
sequence length :
620
specificity :
Rat
purity :
Dopamine Transporter antibody was purified by affinity chromatography.
form :
Lyophilized from PBS with 0.1% BSA. Reconstitute in PBS to a concentration of 1 mg/ml.
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
ELISA: 0.5-1 ug/ml. IHC: 2-10 ug/ml. WB: 1-10 ug/ml
other info1 :
Biological Significance: The dopamine transporter (also known as dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synapse back into cytosol, from which other transporters sequester DA and NE into vesicles for later storage and release. Dopamine reuptake via DAT provides the primary mechanism through which dopamine is cleared from synapses except in the prefrontal cortex, where dopamine uptake via the norepinephrine transporter plays that role.
other info2 :
Immunogen: Dopamine transporter antibody was raised in rabbit using an 18 amino acid peptide of rat DAT conjugated to KLH. as the immunogen.
products categories :
Neuroscience; Purified Polyclonal Antibodies
products description :
Affinity purified Rabbit polyclonal Dopamine Transporter antibody
ncbi gi num :
7108463
ncbi acc num :
AAC50179.2
uniprot acc num :
Q01959
ncbi mol weight :
68,495 Da
ncbi pathways :
Alcoholism Pathway 585563!!Alcoholism Pathway 587116!!Alpha-synuclein Signaling Pathway 137913!!Amphetamine Addiction Pathway 547607!!Amphetamine Addiction Pathway 550546!!Cocaine Addiction Pathway 546258!!Cocaine Addiction Pathway 546273!!Dopamine Clearance From The Synaptic Cleft Pathway 106527!!Dopaminergic Synapse Pathway 469199!!Dopaminergic Synapse Pathway 469185
ncbi summary :
This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009]
size :
0.1 mg
price :
655 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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