This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Desmocollin 2 antibody
catalog :
MBS534473
quantity :
0.1 ml
price :
570 USD
clonality :
polyclonal
host :
guinea pigs
conjugate :
nonconjugated
reactivity :
human, cow
application :
western blot, immunohistochemistry
product information
catalog number :
MBS534473
products type :
Antibody
products full name :
Desmocollin 2 antibody
products short name :
Desmocollin 2
products name syn :
Polyclonal Desmocollin 2; Anti-Desmocollin 2
other names :
desmocollin-2 isoform Dsc2b preproprotein; Desmocollin-2; desmocollin-2; desmocollin 2; Cadherin family member 2; Desmocollin-3; Desmosomal glycoprotein II; Desmosomal glycoprotein III
other gene names :
DSC2; DSC2; DG2; DSC3; CDHF2; ARVD11; DGII/III; CDHF2; DSC3
uniprot entry name :
DSC2_HUMAN
clonality :
Polyclonal
isotype :
IgG1
host :
Guinea Pig
reactivity :
Bovine, Human
sequence length :
847
specificity :
Human desmocollin 2
form :
Supplied as whole antiserum with 0.09% NaN3.
storage stability :
Store at 4 degree C.
tested application :
Immunohistochemistry (IHC), Western Blot (WB)
other info1 :
Biological Significance: Desmocollin-2 is a protein that in humans is encoded by the DSC2 gene. The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Desmocollin 2 antibody was raised in guinea pig using the extracellular part of recombinant human desmocollin 2 as the immunogen.
products categories :
Cell Biology
products description :
Guinea Pig polyclonal Desmocollin 2 antibody
ncbi gi num :
13435366
ncbi acc num :
NP_004940.1
ncbi gb acc num :
NM_004949.3
uniprot acc num :
Q02487
ncbi mol weight :
93,769 Da
ncbi pathways :
Arrhythmogenic Right Ventricular Cardiomyopathy Pathway 672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129
ncbi summary :
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
size :
0.1 ml
price :
570 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!