Oxytocin Receptor antibody | MyBioSource MBS534426 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Oxytocin Receptor antibody

catalog :

MBS534426

quantity :

0.1 mg

price :

675 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS534426

products type :

Antibody

products full name :

Oxytocin Receptor antibody

products short name :

Oxytocin Receptor

products name syn :

Polyclonal Oxytocin Receptor; Anti-Oxytocin Receptor; OTR

other names :

oxytocin receptor; Oxytocin receptor; oxytocin receptor; oxytocin receptor

other gene names :

OXTR; OXTR; OT-R; OT-R

uniprot entry name :

OXYR_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Rat

sequence length :

389

purity :

Oxytocin Receptor antibody was purified by affinity chromatography.

form :

Lyophilized from PBS, with 0.1% BSA, and 0.05% NaN3. Reconstitute in PBS to 1 mg/ml

storage stability :

Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

tested application :

ELISA (EIA), Western Blot (WB)

app notes :

ELISA: 0.5-1 ug/ml. WB: 1-10 ug/ml

other info1 :

Biological Significance: The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. In humans, the oxytocin receptor is encoded by the OXTR gene, which has been localized to human chromosome 3p25. The OXTR protein belongs to the G-protein coupled receptor family, specifically Gq, and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate several different second messenger systems.

other info2 :

Immunogen: Oxytocin receptor antibody was raised in rabbit using a 20 amino acid peptide of rat OTR as the immunogen.

products categories :

Hormones & Steroids

products description :

Rabbit polyclonal Oxytocin Receptor antibody

ncbi gi num :

32307152

ncbi acc num :

NP_000907.2

ncbi gb acc num :

NM_000916.3

uniprot acc num :

P30559

ncbi mol weight :

42,772 Da

ncbi pathways :

Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Myometrial Relaxation And Contraction Pathways (198759); Neuroactive Ligand-receptor Interaction Pathway (83053)

ncbi summary :

The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]

uniprot summary :

OXTR: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1. Chromosomal Location of Human Ortholog: 3p25. Cellular Component: microvillus; cell-cell adherens junction; integral to plasma membrane; apical plasma membrane; plasma membrane. Molecular Function: oxytocin receptor activity; peptide hormone binding; peptide binding; vasopressin receptor activity. Biological Process: lactation; response to peptide hormone stimulus; response to anoxia; heart development; female pregnancy; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; muscle contraction; response to drug; eating behavior; maternal behavior; response to amphetamine; positive regulation of synaptic transmission, GABAergic; social behavior; response to cocaine; sleep; memory; cellular response to hormone stimulus; positive regulation of synaptogenesis; G-protein coupled receptor protein signaling pathway; telencephalon development; suckling behavior; regulation of systemic arterial blood pressure by vasopressin; gut development; response to cytokine stimulus; maternal process involved in parturition; positive regulation of vasoconstriction; sperm ejaculation; response to progesterone stimulus; positive regulation of blood pressure

size1 :

0.1 mg

price1 :

675 USD

more info or order :

MyBioSource product webpage