product summary
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company name :
MyBioSource
product type :
antibody
product name :
Intrinsic Factor antibody
catalog :
MBS534345
quantity :
1 mL
price :
310 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS534345
products type :
Antibody
products full name :
Intrinsic Factor antibody
products short name :
Intrinsic Factor
products name syn :
Polyclonal Intrinsic Factor; Anti-Intrinsic Factor
other names :
intrinsic factor; Gastric intrinsic factor; Intrinsic factor; IF; INF
other gene names :
GIF; IFMH; IF; INF
uniprot entry name :
IF_HUMAN
clonality :
Polyclonal
host :
Rabbit
sequence length :
417
form :
Serum with 0.1% NaN3.
concentration :
1.0ml/ vial
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Biological Significance: Intrinsic factor (IF) also known as gastric intrinsic factor (GIF) is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the terminal ileum. In humans, the gastric intrinsic factor protein is encoded by the GIF gene.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Intrinsic Factor antibody was raised in rabbit using intrinsic factor as the immunogen.
products categories :
Nutrition & Metabolism
products description :
Rabbit polyclonal Intrinsic Factor antibody
ncbi gi num :
183186
ncbi acc num :
AAA66354.1
ncbi mol weight :
42,698 Da
uniprot summary :
GIF: Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis. Defects in GIF are the cause of hereditary intrinsic factor deficiency (IFD); also known as congenital pernicious anemia. IFD is an autosomal recessive disorder characterized by megaloblastic anemia. Belongs to the eukaryotic cobalamin transport proteins family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: extracellular space; lysosomal lumen; microvillus; apical plasma membrane; extracellular region; endosome. Molecular Function: cobalamin binding. Biological Process: vitamin metabolic process; cobalamin metabolic process; cobalamin transport; cobalt ion transport; water-soluble vitamin metabolic process. Disease: Intrinsic Factor Deficiency
size1 :
1 mL
price1 :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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