product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Amylin antibody
catalog :
MBS534339
quantity :
0.05 ml
price :
865 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS534339
products type :
Antibody
products full name :
Amylin antibody
products short name :
Amylin
products name syn :
Polyclonal Amylin; Anti-Amylin
other names :
amylin, partial; Islet amyloid polypeptide; islet amyloid polypeptide; islet amyloid polypeptide; Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptide
other gene names :
IAPP; IAPP; DAP; IAP; DAP
uniprot entry name :
IAPP_HUMAN
clonality :
Polyclonal
isotype :
IgG1
host :
Rabbit
reactivity :
Cat, Guinea Pig, Human, Pig, Rat
sequence length :
62
form :
Lyophilized undiluted rabbit serum. Reconstitute in 50-100 ul of distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.1% Sodium Azide.
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC) Formalin/Paraffin
other info1 :
Biological Significance: Amylin or islet amyloid polypeptide (IAPP) is produced in the pancreas beta cells and coreleased with insulin. The amino acid sequence shows great homology with CGRP. Amylin has been shown to reverse insulin inhibition of hepatic gluconeogenesis and to inhibit muscle uptake of glucose.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Amylin antibody was raised in rabbit using amylin as the immunogen.
products categories :
Hormones & Steroids
products description :
Rabbit polyclonal Amylin antibody
ncbi gi num :
457131
ncbi acc num :
AAA35524.1
uniprot acc num :
P10997
ncbi mol weight :
9,806 Da
ncbi pathways :
Amyloids Pathway 366238!!Calcitonin-like Ligand Receptors Pathway 106379!!Class B/2 (Secretin Family Receptors) Pathway 106378!!Developmental Biology Pathway 477129!!Disease Pathway 530764!!G Alpha (s) Signalling Events Pathway 119549!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Integrated Pancreatic Cancer Pathway 711360!!Maturity Onset Diabetes Of The Young Pathway 83096
ncbi summary :
The protein encoded by this gene is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. This protein also exhibits an bactericidal, antimicrobial activity. [provided by RefSeq, Sep 2014]
size :
0.05 ml
price :
865 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!