product summary
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company name :
MyBioSource
product type :
antibody
product name :
Caspase 3 antibody
catalog :
MBS534167
quantity :
0.05 mg
price :
580 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS534167
products type :
Antibody
products full name :
Caspase 3 antibody
products short name :
Caspase 3
products name syn :
Polyclonal Caspase 3; Anti-Caspase 3; Caspase 3; Cysteine-Aspartic Acid Protease 3; Caspase -3; Caspase-3
other names :
caspase-3 preproprotein; Caspase-3; caspase-3; caspase 3, apoptosis-related cysteine peptidase; Apopain; Cysteine protease CPP32; CPP-32
other gene names :
CASP3; CASP3; CPP32; SCA-1; CPP32B; CPP32; CASP-3; CPP-32; SCA-1
uniprot entry name :
CASP3_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
277
form :
Lyophilized from PBS with 5% trehalose. Reconstitute with 100 ul of PBS with 0.02% NaN3.
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC)
app notes :
IHC: 0.1-0.3 ug/mL
other info1 :
Biological Significance: Caspase 3 is a caspase protein that interacts with caspase 8 and caspase 9. It is encoded by the CASP3 gene. CASP3 orthologs have been identified in numerous mammals for which complete genome data are available. Unique orthologs are also present in birds, lizards, lissamphibians, and teleosts.
other info2 :
Immunogen: Caspase 3 antibody was raised in rabbit using the peptide CRGTELDCGIETD corresponding to amino acids 163-175 of caspase-3 as the immunogen.
products categories :
Cell Cycle & Cell Death
products description :
Rabbit polyclonal Caspase 3 antibody
ncbi gi num :
14790119
ncbi acc num :
NP_004337.2
ncbi gb acc num :
NM_004346.3
uniprot acc num :
P42574
ncbi mol weight :
31,608 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!Activation Of DNA Fragmentation Factor Pathway 105683!!Activation Of Caspases Through Apoptosome-mediated Cleavage Pathway 105672!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Alzheimers Disease Pathway 672448!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Amyotrophic Lateral Sclerosis (ALS) Pathway 920975
ncbi summary :
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
580 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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