product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Calbindin antibody (D28K)
catalog :
MBS534129
quantity :
0.2 ml
price :
685 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, chicken
application :
western blot, immunohistochemistry
more info or order :
product information
catalog number :
MBS534129
products type :
Antibody
products full name :
Calbindin antibody (D28K)
products short name :
Calbindin
products name syn :
Polyclonal Calbindin (D28K); Anti-Calbindin (D28K); D 28K; CAB27; CALB1; CALB; Neuronal Marker; Calbindin D28; D28K; CALB 1; Calbindin 1 28kDa
other names :
calbindin; Calbindin; calbindin; calbindin 1, 28kDa; Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type
other gene names :
CALB1; CALB1; CALB; D-28K; CAB27
uniprot entry name :
CALB1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Chicken, Fish, Human, Monkey, Mouse, Rat Reacts with Calbindin D-28K from Human, Monkey, Rat, Mouse, Chicken, and Fish
sequence length :
261
specificity :
Rat calbindin
form :
Supplied as a lyophilized powder
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -80 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC), Western Blot (WB)
app notes :
IHC: 1:10,000. WB: 1:1,000
other info1 :
Biological Significance: Calbindin D28k is a member of a large family of intracellular calcium binding proteins, containing EF hand calcium binding motifs, and related to calmodulin and troponin C. The biological roles of Calbindin D28k include calcium regulation and calcium dependent signalling in neurons and during development. Decreases in Calbindin D28k abundance, or loss of Calbindin D28k immunoreactivity, is found in models of neurological disorders such as epilepsy, and in neurodegenerative diseases. Calbindin antibody is often used as a marker for cerebellum Purkinje cells.
other info2 :
Immunogen: Calbindin antibody (D28K) was raised in rabbit using recombinant rat Calbindin D-28K as the immunogen.
products categories :
Nutrition & Metabolism
products description :
Rabbit polyclonal Calbindin antibody (D28K)
ncbi gi num :
4826655
ncbi acc num :
NP_004920.1
ncbi gb acc num :
NM_004929.2
uniprot acc num :
P05937
ncbi mol weight :
23,609 Da
ncbi pathways :
Endocrine And Other Factor-regulated Calcium Reabsorption Pathway 213307!!Endocrine And Other Factor-regulated Calcium Reabsorption Pathway 213276
ncbi summary :
The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015]
size :
0.2 ml
price :
685 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!