catalog number :
MBS534006
products full name :
ErbB-2 + HER-2 + Neu antibody
products short name :
ErbB-2 + HER-2 + Neu
products name syn :
Polyclonal ErbB-2 + HER-2 + Neu; Anti-ErbB-2 + HER-2 + Neu; ErbB-2 (HER-2/Neu); ERBB 2; ERBB-2; ERBB2
products gene name :
ErbB-2 + HER-2 + Neu
reactivity :
Monkey, Mouse, Rat
purity :
ErbB-2 + HER-2 + Neu antibody was purified by Protein A chromatography.
form :
Purified IgG supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
concentration :
~1.0 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP), Western Blot (WB)
app notes :
IHC-F: 2.5-5.0 ug/ml. IHC-P: 2.5-5.0 ug/ml. IP: 10 ug/mg protein lysate. WB: 5-10 ug/ml
other info1 :
Biological Significance: c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: ErbB-2/HER-2/Neu antibody was raised in rabbit using a synthetic peptide derived from C-terminus of human c-erbB-2/HER-2 protein as the immunogen.
products categories :
Cancer
products description :
Rabbit polyclonal ErbB-2 + HER-2 + Neu antibody
ncbi mol weight :
185 kDa (predicted detection band MW)