product summary
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company name :
MyBioSource
product type :
antibody
product name :
AURKC antibody
catalog :
MBS533542
quantity :
0.1 mL
price :
725 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[10A7]
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
image
image 1 :
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant AURKC protein (Right) or empty vector (Left) detected with AURKC antibody
image 2 :
Immunohistochemical analysis of AURKC protein in paraffin embedded Human endometrium tissue using AURKC antibody
product information
catalog number :
MBS533542
products type :
Antibody
products full name :
AURKC antibody
products short name :
[AURKC]
products name syn :
[Monoclonal AURKC; Anti-AURKC; Aurora Kinase C; AIE2; AIK3; AurC; STK13; aurora-C]
other names :
[aurora kinase C isoform 3; Aurora kinase C; aurora kinase C; aurora kinase C; Aurora kinase C]
products gene name :
[AURKC]
other gene names :
[AURKC; AURKC; AIE2; AIK3; ARK3; AurC; SPGF5; STK13; HEL-S-90; aurora-C]
uniprot entry name :
Q5Y191_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
[10A7]
host :
Mouse
reactivity :
Human
sequence length :
275
purity :
AURKC antibody was purified by affinity chromatography.
form :
Affinity purified fluid in PBS, pH 7.3 with 1% BSA, 50% Glycerol, and 0.02% NaN 3
concentration :
1.0 mg/mL
storage stability :
4°C shipping. Upon receipt store at -20°C . Avoid repeat freeze-thaw . Stable for 12 months from date of receipt.
tested application :
IF, IHC, WB
app notes :
IF: 1:100. WB: 1:500
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Biological Significance: AURKC may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.
other info2 :
Immunogen: Full length protein expressed in 293T cell transfered with human AURKC expression vector.
products categories :
Signal Transduction
products description :
Mouse monoclonal AURKC antibody
ncbi gi num :
62865643
ncbi acc num :
NP_003151.2
ncbi gb acc num :
NM_003160.2
uniprot acc num :
Q5Y191
ncbi pathways :
Aurora B Signaling Pathway (138080); Aurora C Signaling Pathway (138003); Signaling By Aurora Kinases Pathway (138033)
ncbi summary :
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
uniprot summary :
AurC: a member of the AUR family of kinases. May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. Localized to centrosome from anaphase to cytokinesis. Two splice-variant isoforms have been described. Protein type: Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Protein kinase, Other; Kinase, protein; Other group; AUR family. Chromosomal Location of Human Ortholog: 19q13.43. Cellular Component: spindle microtubule; cytoplasm; spindle; condensed chromosome; spindle pole centrosome; spindle midzone; midbody; condensed nuclear chromosome, pericentric region. Molecular Function: protein serine/threonine/tyrosine kinase activity; histone serine kinase activity; ATP binding; protein kinase activity. Biological Process: positive regulation of cytokinesis; spindle midzone assembly involved in mitosis; meiotic cell cycle; histone modification; regulation of signal transduction; cytokinesis; attachment of spindle microtubules to kinetochore; protein amino acid phosphorylation. Disease: Spermatogenic Failure 5
size1 :
0.1 mL
price1 :
725 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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